| Acetylcholinesterase from Bungarus venom: a monomeric species. | |
MedLine Citation:
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PMID: 8674549 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The venom of Bungarus fasciatus, an Elapidae snake, contains a high level of AChE activity. Partial peptide sequences show that it is closely homologous to other AChEs. Bungarus venom AChE is a non-amphiphilic monomeric species, a molecular form of AChE which has not been previously found in significant levels in other tissues. The composition of carbohydrates suggests the presence of N-glycans of the 'complex' and 'hybrid' types. Ion exchange chromatography, isoelectric focusing and electrophoresis in non-denaturing and denaturing conditions reveal a complex microheterogeneity of this enzyme, which is partly related to its glycosylation. |
Authors:
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X Cousin; C Créminon; J Grassi; K Méflah; G Cornu; B Saliou; S Bon; J Massoulié; C Bon |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: FEBS letters Volume: 387 ISSN: 0014-5793 ISO Abbreviation: FEBS Lett. Publication Date: 1996 Jun |
Date Detail:
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Created Date: 1996-08-15 Completed Date: 1996-08-15 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0155157 Medline TA: FEBS Lett Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 196-200 Citation Subset: IM |
Affiliation:
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Unité des Venins, Institut Pasteur, Paris, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acetylcholinesterase
/
analysis*,
chemistry,
toxicity Amino Acid Sequence Animals Bungarotoxins / chemistry*, toxicity Bungarus* Carbohydrates / analysis Electrochemistry Male Mice Molecular Sequence Data Sequence Homology, Amino Acid |
| Chemical | |
Reg. No./Substance:
|
0/Bungarotoxins; 0/Carbohydrates; EC 3.1.1.7/Acetylcholinesterase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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