Document Detail


Acetylation phenotype and skin complexion.
MedLine Citation:
PMID:  2430405     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The relationship of acetylation phenotype to skin complexion was studied in 155 healthy Caucasians. Individuals received 500 mg sulphadimidine at 11.00 p.m.; urine was collected eight hours later. The percentage of acetylated sulphadimidine in urine was measured with high performance liquid chromatography. There was a slight but insignificant preponderance of slow acetylators in the dark skin types. It is concluded that slow acetylation phenotype is not correlated with light skin complexion. Therefore, it is unlikely that acetylation of xenobiotic carcinogens plays a dominant role in melanoma risk.
Authors:
F H Rampen; H L van der Meeren; L M Stolk
Related Documents :
22763235 - Exposure of beef females to the biostimulatory effects of bulls with or without deposit...
3350195 - Protein/creatinine ratio in the assessment of proteinuria during pregnancy.
23146315 - Pregnancy loss and anxiety and depression during subsequent pregnancies: data from the ...
1137335 - Hepatotis of pregnancy. a clinical study of 107 patients.
9124335 - Ovine fetal leucine kinetics and protein metabolism during acute metabolic acidosis.
18460625 - Pseudomonas-associated discospondylitis in a two-month-old llama.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta dermato-venereologica     Volume:  66     ISSN:  0001-5555     ISO Abbreviation:  Acta Derm. Venereol.     Publication Date:  1986  
Date Detail:
Created Date:  1986-12-02     Completed Date:  1986-12-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370310     Medline TA:  Acta Derm Venereol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  334-6     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acetyltransferases / metabolism*
Adult
Female
Humans
Male
Melanoma / etiology
Phenotype
Risk
Skin Neoplasms / etiology
Skin Pigmentation*
Sulfamethazine / metabolism*,  urine
Chemical
Reg. No./Substance:
57-68-1/Sulfamethazine; EC 2.3.1.-/Acetyltransferases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Analysis of serovar distribution as a tool in epidemiological studies in gonorrhoea.
Next Document:  The regulation of subcutaneous blood flow in patient with Dercum's disease.