| Acetylation phenotype and skin complexion. | |
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MedLine Citation:
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PMID: 2430405 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The relationship of acetylation phenotype to skin complexion was studied in 155 healthy Caucasians. Individuals received 500 mg sulphadimidine at 11.00 p.m.; urine was collected eight hours later. The percentage of acetylated sulphadimidine in urine was measured with high performance liquid chromatography. There was a slight but insignificant preponderance of slow acetylators in the dark skin types. It is concluded that slow acetylation phenotype is not correlated with light skin complexion. Therefore, it is unlikely that acetylation of xenobiotic carcinogens plays a dominant role in melanoma risk. |
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Authors:
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F H Rampen; H L van der Meeren; L M Stolk |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Acta dermato-venereologica Volume: 66 ISSN: 0001-5555 ISO Abbreviation: Acta Derm. Venereol. Publication Date: 1986 |
Date Detail:
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Created Date: 1986-12-02 Completed Date: 1986-12-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370310 Medline TA: Acta Derm Venereol Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 334-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acetyltransferases
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metabolism* Adult Female Humans Male Melanoma / etiology Phenotype Risk Skin Neoplasms / etiology Skin Pigmentation* Sulfamethazine / metabolism*, urine |
| Chemical | |
Reg. No./Substance:
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57-68-1/Sulfamethazine; EC 2.3.1.-/Acetyltransferases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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