Document Detail

Acetyl salicylic acid induced-urticaria and/or angioedema in atopic children.
MedLine Citation:
PMID:  3381713     Owner:  NLM     Status:  MEDLINE    
From the report of Hirschberg, only 3 years after aspirin synthesis, there have been numerous works dedicated to showing the different types of adverse reactions found following aspirin administration. However, there are few publications on the process of urticaria and/or acute angioedema induced by ASA and few reported cases were found in children. Thus, we present 6 atopic children with urticaria and/or angioedema related with ASA. A carefully detailed history, oral provocation with ASA, oral provocation with other NSAI and HBDT with ASA were done to all of them. The oral provocation with ASA was positive in 5 of the 6 cases. The provocations with the rest of the NSAI and tartrazine and sodium benzoate were negative in all of the patients. The HBDT was positive in 5 of the cases. In conclusion, we insist that aspirin intolerance is not infrequent in infancy and it is not rare to see urticaria and or angioedema, in spite of the fact that asthmatics, atopics or non atopics, usually present as bronchospasm. We also believe that the HBDT can be a method of diagnosis used in these cases.
J Botey; C Navarro; C Aulesa; A Marín; J L Eseverri
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Allergologia et immunopathologia     Volume:  16     ISSN:  0301-0546     ISO Abbreviation:  Allergol Immunopathol (Madr)     Publication Date:    1988 Jan-Feb
Date Detail:
Created Date:  1988-07-15     Completed Date:  1988-07-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370073     Medline TA:  Allergol Immunopathol (Madr)     Country:  SPAIN    
Other Details:
Languages:  eng     Pagination:  43-7     Citation Subset:  IM    
Servicio de Alergia e Inmunologia Clinica, Hospital Infantil de La Vall D'Hebron, Universidad Autonoma de Barcelona, Spain.
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MeSH Terms
Angioedema / chemically induced*
Aspirin / adverse effects*
Asthma / chemically induced
Child, Preschool
Rhinitis, Allergic, Perennial / chemically induced
Urticaria / chemically induced*
Reg. No./Substance:

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