Document Detail


Acetate formation after short-term ethanol administration in man.
MedLine Citation:
PMID:  4063075     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of an acute oral load of 0.5 g ethanol/kg body weight was studied in a group of 10 healthy male and one of 10 healthy female individuals. The following parameters were measured in the blood between 0 and 7 h after the start of the experiment: ethanol, acetate, glucose, free fatty acids, free glycerol, lactate, pyruvate, 3-hydroxybutyrate, acetoacetate. While the elimination of ethanol followed zero-order kinetics between 2 and 5 h, a steady-state concentration of 0.4 to 0.6 mM acetate in the serum was observed during the same time interval. Concomitantly, a significant decrease of free fatty acid and free glycerol concentrations was observed.
Authors:
D Hannak; U Bartelt; R Kattermann
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biological chemistry Hoppe-Seyler     Volume:  366     ISSN:  0177-3593     ISO Abbreviation:  Biol. Chem. Hoppe-Seyler     Publication Date:  1985 Aug 
Date Detail:
Created Date:  1986-01-08     Completed Date:  1986-01-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8503054     Medline TA:  Biol Chem Hoppe Seyler     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  749-53     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Acetaldehyde / metabolism
Acetic Acid
Acetic Acids / metabolism*
Adult
Child
Ethanol / metabolism*
Fatty Acids, Nonesterified / metabolism
Female
Glycerol / metabolism
Humans
Oxidation-Reduction
Sex Factors
Chemical
Reg. No./Substance:
0/Acetic Acids; 0/Fatty Acids, Nonesterified; 56-81-5/Glycerol; 64-17-5/Ethanol; 64-19-7/Acetic Acid; 75-07-0/Acetaldehyde

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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