| Acetate formation after short-term ethanol administration in man. | |
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MedLine Citation:
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PMID: 4063075 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of an acute oral load of 0.5 g ethanol/kg body weight was studied in a group of 10 healthy male and one of 10 healthy female individuals. The following parameters were measured in the blood between 0 and 7 h after the start of the experiment: ethanol, acetate, glucose, free fatty acids, free glycerol, lactate, pyruvate, 3-hydroxybutyrate, acetoacetate. While the elimination of ethanol followed zero-order kinetics between 2 and 5 h, a steady-state concentration of 0.4 to 0.6 mM acetate in the serum was observed during the same time interval. Concomitantly, a significant decrease of free fatty acid and free glycerol concentrations was observed. |
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Authors:
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D Hannak; U Bartelt; R Kattermann |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Biological chemistry Hoppe-Seyler Volume: 366 ISSN: 0177-3593 ISO Abbreviation: Biol. Chem. Hoppe-Seyler Publication Date: 1985 Aug |
Date Detail:
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Created Date: 1986-01-08 Completed Date: 1986-01-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8503054 Medline TA: Biol Chem Hoppe Seyler Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 749-53 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acetaldehyde
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metabolism Acetic Acid Acetic Acids / metabolism* Adult Child Ethanol / metabolism* Fatty Acids, Nonesterified / metabolism Female Glycerol / metabolism Humans Oxidation-Reduction Sex Factors |
| Chemical | |
Reg. No./Substance:
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0/Acetic Acids; 0/Fatty Acids, Nonesterified; 56-81-5/Glycerol; 64-17-5/Ethanol; 64-19-7/Acetic Acid; 75-07-0/Acetaldehyde |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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