Document Detail

Acetaminophen and aspirin. Prescription, use, and accidental ingestion among children.
MedLine Citation:
PMID:  7124704     Owner:  NLM     Status:  MEDLINE    
Among 3,587 hospitalized children monitored by the Pediatric Drug Surveillance Program between 1974 and 1979, acetaminophen was prescribed for 32% and aspirin for 3%. In the three months before admission, 23% reported use of either drug. In both inpatient and preadmission settings, acetaminophen use increased between 1975 and 1977 and decreased subsequently. Aspirin prescriptions were consistent over the entire study period among inpatients, but preadmission use decreased substantially. The Massachusetts Poison Information Center observed a 36% increase in calls concerning aspirin from 1976 to 1977 and 1977 to 1978, similar to the increase in all calls, but acetaminophen calls increased by 87%. Long-standing concerns about the toxic effects of aspirin, coupled with recent concerns about hepatotoxic effects of acetaminophen in overdose, may be leading physicians and parents to decrease the use of both drugs for the treatment of fever.
A A Mitchell; F H Lovejoy; D Slone; S Shapiro
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of diseases of children (1960)     Volume:  136     ISSN:  0002-922X     ISO Abbreviation:  Am. J. Dis. Child.     Publication Date:  1982 Nov 
Date Detail:
Created Date:  1982-12-03     Completed Date:  1982-12-03     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0370471     Medline TA:  Am J Dis Child     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  976-9     Citation Subset:  AIM; IM    
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MeSH Terms
Acetaminophen / poisoning*
Aspirin / poisoning*
Child, Preschool
Drug Prescriptions*
Drug Utilization*
Fever / drug therapy
Headache / drug therapy
Infant, Newborn
Pain / drug therapy
Grant Support
Reg. No./Substance:
103-90-2/Acetaminophen; 50-78-2/Aspirin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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