Document Detail

Acetabular Cartilage Assessment in Patients with Femoroacetabular Impingement by Using T2* Mapping with Arthroscopic Verification.
MedLine Citation:
PMID:  24520945     Owner:  NLM     Status:  Publisher    
Purpose To evaluate the ability of T2* mapping to help differentiate damaged from normal acetabular cartilage in patients with femoroacetabular impingement (FAI). Materials and Methods The institutional review board approved this retrospective study, and the requirement to obtain informed consent was waived. The study complied with HIPAA guidelines. The authors reviewed T2* relaxation time maps of 28 hips from 26 consecutive patients (mean patient age, 28.2 years; range, 12-53 years; eight male patients (nine hips) with a mean age of 26.7 years [range, 16-53 years]; 18 female patients (19 hips) with a mean age of 28.9 years [range, 12-46 years]). Conventional diagnostic 3.0-T magnetic resonance (MR) arthrography was augmented by including a multiecho gradient-recalled echo sequence for T2* mapping. After imaging, acetabular and femoral data were separated and acetabular regions of interest were identified. Arthroscopic cartilage assessment with use of a modified Beck scale for acetabular cartilage damage was performed by an orthopedic surgeon who was blinded to the results of T2* mapping. A patient-specific acetabular projection with a T2* overlay was developed to anatomically correlate imaging data with those from surgery (the standard of reference). Results were analyzed by using receiver operating characteristic (ROC) curves. Results The patient-specific acetabular projection enabled colocalization between the MR imaging and arthroscopic findings. T2* relaxation times for normal cartilage (Beck score 1, 35.3 msec ± 7.0) were significantly higher than those for cartilage with early changes (Beck score 2, 20.7 msec ± 6.0) and cartilage with more advanced degeneration (Beck scores 3-6, ≤19.8 msec ± 5.6) (P < .001). At ROC curve analysis, a T2* value of 28 msec was identified as the threshold for damaged cartilage, with a 91% true-positive and 13% false-positive rate for differentiating Beck score 1 cartilage (normal) from all other cartilages. Conclusion The patient-specific acetabular projection with a T2* mapping overlay enabled good anatomic localization of cartilage damage defined with a T2* threshold of 28 msec and less. © RSNA, 2014.
Jutta Ellermann; Connor Ziegler; Mikko J Nissi; Rainer Goebel; John Hughes; Michael Benson; Peter Holmberg; Patrick Morgan
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-2-8
Journal Detail:
Title:  Radiology     Volume:  -     ISSN:  1527-1315     ISO Abbreviation:  Radiology     Publication Date:  2014 Feb 
Date Detail:
Created Date:  2014-2-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  131837     Citation Subset:  -    
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