Document Detail


Acellular and glutaraldehyde-preserved tendon allografts for reconstruction of superficial digital flexor tendon in bovines: Part I--Clinical, radiological and angiographical observations.
MedLine Citation:
PMID:  15157019     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sixteen tenorrhaphies were performed at the mid-metatarsal region in eight buffalo calves under lignocaine epidural analgesia. A 2 cm long gap was created in the superficial digital flexor (SDF) tendon and immediately repaired with acellular grafts in animals of group I, 1% glutaraldehyde-preserved tendon allografts in group II. In group III, the defect was repaired with autografts. This group served as control. The contralateral limb in each animal was operated after an interval of 60 days and the animals underwent the same procedure according to the designed groups. Diclofenac sodium and Enrofloxacin was given post-operatively for 5 days. Clinical examination revealed significant increase (P < 0.05) in rectal temperature, heart and respiratory rate for 3-4 postoperative days in all the animals. Mild pain and exudation as well as early restoration of tendon gliding movements and weight-bearing were observed earlier in group I in comparison with group II. Air-tendograms revealed early organization, minimal adhesion formation and lesser thickening of tendon at the reconstructive site in the acellular group whereas in the glutaraldehyde group dense homogenous swelling with adhesions was seen along the flexors. Angiography on day 30 showed that the area of proximal and distal host tendon graft junction appeared hypervascularized, whereas the area occupied by the graft appeared relatively less vascularized. Normal vascularization was observed on day 90 in all the three groups.
Authors:
R Ramesh; N Kumar; A K Sharma; S K Maiti; G R Singh
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of veterinary medicine. A, Physiology, pathology, clinical medicine     Volume:  50     ISSN:  0931-184X     ISO Abbreviation:  J Vet Med A Physiol Pathol Clin Med     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2004-05-25     Completed Date:  2004-06-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100955112     Medline TA:  J Vet Med A Physiol Pathol Clin Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  511-9     Citation Subset:  IM    
Affiliation:
Division of Surgery, Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, India.
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MeSH Terms
Descriptor/Qualifier:
Angiography / veterinary
Animals
Animals, Newborn
Buffaloes / injuries,  surgery*
Glutaral
Hindlimb / pathology,  radiography,  surgery
Male
Tendon Injuries / pathology,  radiography,  surgery,  veterinary*
Tendons / radiography,  transplantation*
Tissue Preservation / veterinary
Transplantation, Homologous / pathology,  veterinary
Wound Healing
Chemical
Reg. No./Substance:
111-30-8/Glutaral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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