| Accurate measurement of left ventricular ejection fraction by three-dimensional echocardiography. A comparison with radionuclide angiography. | |
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MedLine Citation:
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PMID: 8759089 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Three-dimensional echocardiography is a promising technique for calculation of left ventricular ejection fraction, because it allows its measurement without geometric assumptions. However, few data exist that study its reproducibility and accuracy in patients. METHODS AND RESULTS: Twenty-five patients underwent radionuclide angiography and three-dimensional echocardiography that used the rotational technique (2 degrees interval and ECG and respiratory gating). Left ventricular volume and ejection fraction were calculated by use of Simpson's rule at a slice thickness of 3 mm. Analyses were performed to define the largest slice thickness required for accurate calculation of left ventricular volume and ejection fraction. Three-dimensional echocardiography showed excellent correlation with radionuclide angiography for calculation of left ventricular ejection fraction (mean +/- SD, 38.9 +/- 19.8 and 38.5 +/- 18.0, respectively; r = .99); their mean difference was not significant (0.03 +/- 0.17; P = .3), and they had a close limit of agreement (-0.385, 0.315). Intraobserver variability for radionuclide angiography and three-dimensional echocardiography was 4.2% and 2.6%, respectively, whereas interobserver variability was 6.2% and 5.3%, respectively. There was no significant difference between left ventricular volume and ejection fraction calculated at a slice thickness of 3 mm and that calculated at different slice thicknesses up to 24 mm. However, the standard deviation of the mean difference showed a stepwise increase, particularly at thicknesses > 15 mm. At a slice thickness of 15 mm, the probability of three-dimensional echocardiography to detect > or = 6% difference in ejection fraction was 80%. CONCLUSIONS: Three-dimensional echocardiography has excellent correlation with radionuclide angiography for calculation of left ventricular ejection fraction in patients and has an observer variability similar to that of radionuclide angiography. We recommend the use of a 15-mm-thick slice for accurate and rapid measurement of left ventricular volume and ejection fraction. |
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Authors:
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Y F Nosir; P M Fioretti; W B Vletter; E Boersma; A Salustri; J T Postma; A E Reijs; F J Ten Cate; J R Roelandt |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Circulation Volume: 94 ISSN: 0009-7322 ISO Abbreviation: Circulation Publication Date: 1996 Aug |
Date Detail:
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Created Date: 1996-12-11 Completed Date: 1996-12-11 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0147763 Medline TA: Circulation Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 460-6 Citation Subset: AIM; IM |
Affiliation:
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Thoraxcenter, Division of Cardiology, University Hospital, Rotterdam-Dijkzigt, Netherlands. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Blood Volume Echocardiography* Feasibility Studies Female Humans Image Processing, Computer-Assisted Male Middle Aged Observer Variation Radionuclide Angiography* Reproducibility of Results Stroke Volume* Ventricular Function, Left |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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