| Accurate analysis of urea in milk and milk powder by isotope dilution gas chromatography-mass spectrometry. | |
| | |
MedLine Citation:
|
PMID: 20434964 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A high order method for measuring urea concentrations in milk and milk powder was developed. The method can be applied to certify the concentration of urea in some new milk and milk powder CRMs. This high accurate method for analysis of milk is valuable given the inherent challenges associated with the complexity of the sample matrix. A measurement procedure based on gas chromatography/isotope dilution mass spectrometry (GC/IDMS) was developed. Samples were pre-treated with acetonitrile to remove proteins and the method was applied to determine urea concentrations in milk and milk powder. Excellent precision was obtained, with within- and between-set coefficients of variation of 0.15-0.46 and 0.18-0.65%, respectively. The measurement uncertainty is evaluated. The method can trace to mass. |
| | |
Authors:
|
Xinhua Dai; Xiang Fang; Fuhai Su; Mengrui Yang; Hongmei Li; Jian Zhou; Ruifeng Xu |
Related Documents
:
|
18759194 - Increased aflatoxin contamination of dried figs in a drought year. 22405294 - Electrochemical stripping analysis of nanogold label-induced silver deposition for ultr... 17181994 - Methods for the quantitation of human milk oligosaccharides in bacterial fermentation b... 12537424 - Methodology for quantifying residues of chlorhexidine in raw dairy milk. 10410924 - Novel high-performance liquid chromatographic and solid-phase extraction methods for qu... 3358834 - Rear seat restraint system effectiveness in preventing fatalities. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-04-14 |
Journal Detail:
|
Title: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Volume: 878 ISSN: 1873-376X ISO Abbreviation: J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. Publication Date: 2010 Jun |
Date Detail:
|
Created Date: 2010-05-17 Completed Date: 2010-08-26 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101139554 Medline TA: J Chromatogr B Analyt Technol Biomed Life Sci Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 1634-8 Citation Subset: IM |
Copyright Information:
|
Copyright 2010 Elsevier B.V. All rights reserved. |
Affiliation:
|
National Institute of Metrology, No. 18 Beisanhuan Donglu, Chaoyang Dist, Beijing 100013, PR China. xhdai_75@iccas.ac.cn |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acetonitriles Animals Gas Chromatography-Mass Spectrometry / methods* Isotope Labeling / methods* Linear Models Methanol Milk / chemistry* Reproducibility of Results Sensitivity and Specificity Urea / analysis* |
| Chemical | |
Reg. No./Substance:
|
0/Acetonitriles; 57-13-6/Urea; 67-56-1/Methanol; 75-05-8/acetonitrile |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Dyslipidaemia-Hepatic and intestinal cross-talk.
Next Document: An infrequent cause of hypopotassemia in a patient with longstanding hypertension.