Document Detail


Accuracy of the triglyceride to high-density lipoprotein cholesterol ratio for prediction of the low-density lipoprotein phenotype B.
MedLine Citation:
PMID:  15246907     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study examined the accuracy of a triglyceride/high-density lipoprotein (HDL) cholesterol ratio of 3.8 for the prediction of low-density lipoprotein (LDL) phenotype B. The ratio of 3.8 was based on Adult Treatment Panel recommendations for normal fasting triglycerides (<150 mg/dl) and HDL cholesterol (>40 mg/dl). Fasting blood samples were obtained from 658 patients. LDL phenotype analysis was performed by nuclear magnetic resonance spectroscopy. A triglyceride/HDL cholesterol ratio of 3.8 divided the distribution of LDL phenotypes with 79% (95% confidence interval [CI] 74 to 83) of phenotype B greater than and 81% (95% CI 77 to 85) of phenotype A less than the ratio of 3.8. The ratio was reliable for identifying LDL phenotype B in men and women.
Authors:
Viktor Hanak; Julian Munoz; Joe Teague; Alfred Stanley; Vera Bittner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  94     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-07-12     Completed Date:  2004-08-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  219-22     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, Carraway Methodist Medical Center, Birmingham, Alabama, USA. vhanak49@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Cholesterol, HDL / blood*
Cholesterol, LDL / genetics*
Female
Humans
Logistic Models
Magnetic Resonance Spectroscopy
Male
Middle Aged
Particle Size
Phenotype
Sensitivity and Specificity
Triglycerides / blood*
Chemical
Reg. No./Substance:
0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Triglycerides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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