Document Detail

Accuracy of transcutaneous carbon dioxide tension measurements during cardiopulmonary exercise testing.
MedLine Citation:
PMID:  19088464     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Measurements of transcutaneous carbon dioxide tension (PtcCO(2)) with current devices are proven to provide clinically acceptable agreement with measurements of partial arterial carbon dioxide tension (PaCO(2)) in several settings but not during cardiopulmonary exercise testing (CPET). OBJECTIVES: The primary objective of this study was to investigate the agreement between PaCO(2) and PtcCO(2) measurements (using a Tosca 500 with a Tosca sensor 92) during CPET. A secondary objective was to investigate the agreement between arterial and transcutaneous oxygen saturation (SaO(2), SpO(2)) as measured with this sensor during CPET. METHODS: In patients with various pulmonary diseases, PtcCO(2) and SpO(2) were continuously measured and compared with arterial blood gas samples during CPET. A maximum bias of 0.5 kPa and 95% limits of agreement (LOA) of 1 kPa between carbon dioxide pressure (PCO(2)) measurements were determined as clinically acceptable. RESULTS: In total 101 'paired' arterial and transcutaneous measurements were obtained from 21 patients. Bias between PaCO(2) and PtcCO(2) was -0.03 kPa with LOA from -0.78 to 0.71 kPa. Bias between SaO(2) and SpO(2) was -1.0% with LOA from -2.83 to 0.83%. CONCLUSIONS: Transcutaneous estimations of PCO(2) and SpO(2) are accurate and can be used in CPET, circumvening the need for arterial cannulation.
Gerben Stege; Frank J J van den Elshout; Yvonne F Heijdra; Marjo J T van de Ven; P N Richard Dekhuijzen; Petra J E Vos
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-12-17
Journal Detail:
Title:  Respiration; international review of thoracic diseases     Volume:  78     ISSN:  1423-0356     ISO Abbreviation:  Respiration     Publication Date:  2009  
Date Detail:
Created Date:  2009-07-24     Completed Date:  2009-10-14     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0137356     Medline TA:  Respiration     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  147-53     Citation Subset:  IM    
Department of Pulmonology, Rijnstate Hospital, NL-6800 TA Arnhem, The Netherlands.
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MeSH Terms
Blood Gas Monitoring, Transcutaneous*
Exercise Test*
Heart Rate
Middle Aged
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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