Document Detail


Accuracy of a semi-quantitative urine pregnancy test compared to serum beta-hCG measurement: a possible screening tool for ongoing pregnancy after medication abortion.
MedLine Citation:
PMID:  17656178     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: Medication abortion protocols commonly rely on ultrasound or serum hCG measurement to confirm completion. In order to explore the use of a urine-based test to screen for ongoing pregnancy, we compared the diagnostic accuracy of a recently developed semi-quantitative urine pregnancy test to serum beta-hCG testing. METHODS: We evaluated the urine test with 97 women in early pregnancy at a hospital and private clinic in Mexico City. The results of the urine test (hCG level > or <1000 IU/L) were correlated with those of a serum quantitative beta-hCG immunoradiometric assay. RESULTS: The sensitivity of the urine test to identify individuals with a serum beta-hCG level >1000 IU/L was 88.6% (95% CI 74.6- 95.7%), and its specificity was 71.7% (95% CI 57.4-82.8%). CONCLUSION: The reasonably high sensitivity of this urine test suggests it might be useful as a screening test to detect ongoing pregnancy after medication abortion. Future research should evaluate its utility in clinical follow-up protocols.
Authors:
Daniel Grossman; Karla Berdichevsky; Fernando Larrea; Jorge Beltran
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article     Date:  2007-06-18
Journal Detail:
Title:  Contraception     Volume:  76     ISSN:  0010-7824     ISO Abbreviation:  Contraception     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-07-27     Completed Date:  2008-01-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0234361     Medline TA:  Contraception     Country:  United States    
Other Details:
Languages:  eng     Pagination:  101-4     Citation Subset:  IM    
Affiliation:
Ibis Reproductive Health, c/o Department of Obstetrics and Gynecology, San Francisco General Hospital, San Francisco, CA 94110, USA. dgrossman@ibisreproductivehealth.org
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MeSH Terms
Descriptor/Qualifier:
Abortion, Induced
Chorionic Gonadotropin, beta Subunit, Human / blood*,  urine*
Female
Humans
Pregnancy
Pregnancy Tests / standards*
Prospective Studies
Treatment Failure
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin, beta Subunit, Human

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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