| Accuracy of a semi-quantitative urine pregnancy test compared to serum beta-hCG measurement: a possible screening tool for ongoing pregnancy after medication abortion. | |
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MedLine Citation:
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PMID: 17656178 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: Medication abortion protocols commonly rely on ultrasound or serum hCG measurement to confirm completion. In order to explore the use of a urine-based test to screen for ongoing pregnancy, we compared the diagnostic accuracy of a recently developed semi-quantitative urine pregnancy test to serum beta-hCG testing. METHODS: We evaluated the urine test with 97 women in early pregnancy at a hospital and private clinic in Mexico City. The results of the urine test (hCG level > or <1000 IU/L) were correlated with those of a serum quantitative beta-hCG immunoradiometric assay. RESULTS: The sensitivity of the urine test to identify individuals with a serum beta-hCG level >1000 IU/L was 88.6% (95% CI 74.6- 95.7%), and its specificity was 71.7% (95% CI 57.4-82.8%). CONCLUSION: The reasonably high sensitivity of this urine test suggests it might be useful as a screening test to detect ongoing pregnancy after medication abortion. Future research should evaluate its utility in clinical follow-up protocols. |
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Authors:
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Daniel Grossman; Karla Berdichevsky; Fernando Larrea; Jorge Beltran |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article Date: 2007-06-18 |
Journal Detail:
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Title: Contraception Volume: 76 ISSN: 0010-7824 ISO Abbreviation: Contraception Publication Date: 2007 Aug |
Date Detail:
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Created Date: 2007-07-27 Completed Date: 2008-01-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0234361 Medline TA: Contraception Country: United States |
Other Details:
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Languages: eng Pagination: 101-4 Citation Subset: IM |
Affiliation:
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Ibis Reproductive Health, c/o Department of Obstetrics and Gynecology, San Francisco General Hospital, San Francisco, CA 94110, USA. dgrossman@ibisreproductivehealth.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Induced Chorionic Gonadotropin, beta Subunit, Human / blood*, urine* Female Humans Pregnancy Pregnancy Tests / standards* Prospective Studies Treatment Failure |
| Chemical | |
Reg. No./Substance:
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0/Chorionic Gonadotropin, beta Subunit, Human |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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