| Accuracy and reproducibility of telecytology diagnosis of cervical smears. A tool for quality assurance programs. | |
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MedLine Citation:
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PMID: 12645336 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We randomly selected 50 cervical smears (benign, 14; atypical squamous cells of undetermined significance [ASCUS], 5; low-grade squamous intraepithelial lesion [LSIL], 10; high-grade squamous intraepithelial lesion (HSIL), 12; squamous cell carcinoma, 6; adenocarcinoma, 3) and captured 1,181 digital images (518 MB) at a maximum resolution of 1,600 x 1,200 pixels and transmitted them by e-mail. Diagnosis of glass slides and digital images was done independently in a double-blind manner by 3 pathologists and 3 cytotechnologists, commencing with the diagnosis of digital images followed by diagnosis of glass slides 3 months later. The procedure was repeated after 3 months. Diagnoses were recorded as benign, ASCUS or atypical glandular cells of undetermined significance, LSIL, HSIL, squamous cell carcinoma or adenocarcinoma, and "inadequate for diagnosis." Diagnostic accuracy and interobserver reproducibility were analyzed using an intraclass correlation coefficient (ICC), which revealed good interobserver agreement for the first (0.72) and second (0.64) glass slide diagnoses and the first (0.72) and second (0.60) digital image diagnoses. The kappa values for intraobserver variation between first and second glass slide diagnoses and first and second digital image diagnoses showed moderate to excellent agreement. Digital images are suitable substitutes for glass slides; telecytology can be used as an alternative method for the cytologic diagnosis of cervical smears, particularly in quality assurance programs. |
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Authors:
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Eung Seok Lee; In Sun Kim; Jong Sang Choi; Bom Woo Yeom; Han Kyeom Kim; Jong Ho Han; Mi Sook Lee; Anthony S Y Leong |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: American journal of clinical pathology Volume: 119 ISSN: 0002-9173 ISO Abbreviation: Am. J. Clin. Pathol. Publication Date: 2003 Mar |
Date Detail:
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Created Date: 2003-03-20 Completed Date: 2003-04-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370470 Medline TA: Am J Clin Pathol Country: United States |
Other Details:
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Languages: eng Pagination: 356-60 Citation Subset: AIM; IM |
Affiliation:
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Division of Anatomical Pathology, Hunter Area Pathology Service and Discipline of Anatomical Pathology, University of Newcastle, Newcastle, New South Wales, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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diagnosis Carcinoma, Squamous Cell / diagnosis Cervical Intraepithelial Neoplasia / diagnosis Consensus Double-Blind Method Female Humans Observer Variation Quality Assurance, Health Care* Random Allocation Reproducibility of Results Signal Processing, Computer-Assisted Telepathology / methods* Time Factors Uterine Cervical Dysplasia / diagnosis Uterine Cervical Neoplasms / diagnosis Vaginal Smears / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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