Document Detail

Accuracy and reproducibility of telecytology diagnosis of cervical smears. A tool for quality assurance programs.
MedLine Citation:
PMID:  12645336     Owner:  NLM     Status:  MEDLINE    
We randomly selected 50 cervical smears (benign, 14; atypical squamous cells of undetermined significance [ASCUS], 5; low-grade squamous intraepithelial lesion [LSIL], 10; high-grade squamous intraepithelial lesion (HSIL), 12; squamous cell carcinoma, 6; adenocarcinoma, 3) and captured 1,181 digital images (518 MB) at a maximum resolution of 1,600 x 1,200 pixels and transmitted them by e-mail. Diagnosis of glass slides and digital images was done independently in a double-blind manner by 3 pathologists and 3 cytotechnologists, commencing with the diagnosis of digital images followed by diagnosis of glass slides 3 months later. The procedure was repeated after 3 months. Diagnoses were recorded as benign, ASCUS or atypical glandular cells of undetermined significance, LSIL, HSIL, squamous cell carcinoma or adenocarcinoma, and "inadequate for diagnosis." Diagnostic accuracy and interobserver reproducibility were analyzed using an intraclass correlation coefficient (ICC), which revealed good interobserver agreement for the first (0.72) and second (0.64) glass slide diagnoses and the first (0.72) and second (0.60) digital image diagnoses. The kappa values for intraobserver variation between first and second glass slide diagnoses and first and second digital image diagnoses showed moderate to excellent agreement. Digital images are suitable substitutes for glass slides; telecytology can be used as an alternative method for the cytologic diagnosis of cervical smears, particularly in quality assurance programs.
Eung Seok Lee; In Sun Kim; Jong Sang Choi; Bom Woo Yeom; Han Kyeom Kim; Jong Ho Han; Mi Sook Lee; Anthony S Y Leong
Related Documents :
18283986 - Digital image processing.
23400066 - High-resolution spectral imaging based on coded dispersion.
24562266 - Structured illumination diffraction phase microscopy for broadband, subdiffraction reso...
23676236 - Ultra-widefield imaging of duchenne muscular dystrophy-associated proliferative retinal...
18530646 - Imaging of large-scale sediment transport dynamics with multibeam sonar.
23878526 - Sample training based wildfire segmentation by 2d histogram θ-division with minimum er...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  119     ISSN:  0002-9173     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-03-20     Completed Date:  2003-04-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  356-60     Citation Subset:  AIM; IM    
Division of Anatomical Pathology, Hunter Area Pathology Service and Discipline of Anatomical Pathology, University of Newcastle, Newcastle, New South Wales, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Adenocarcinoma / diagnosis
Carcinoma, Squamous Cell / diagnosis
Cervical Intraepithelial Neoplasia / diagnosis
Double-Blind Method
Observer Variation
Quality Assurance, Health Care*
Random Allocation
Reproducibility of Results
Signal Processing, Computer-Assisted
Telepathology / methods*
Time Factors
Uterine Cervical Dysplasia / diagnosis
Uterine Cervical Neoplasms / diagnosis
Vaginal Smears / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Steroid hormone regulation and prognostic value of the human kallikrein gene 14 in ovarian cancer.
Next Document:  Immunoreactivity of Hep Par 1 in hepatic and extrahepatic tumors and its correlation with albumin in...