| Accuracy and reproducibility of 12-h esophageal pH monitoring. | |
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MedLine Citation:
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PMID: 2051266 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Seventy-five consecutive 24-h intraesophageal pH recordings performed according to the methods of Jolley et al. were evaluated. Total scores and the mean duration of sleep reflux (ZMD) were calculated for the first and the last 12 h, respectively, and compared to each other, as well as to the full 24-h recording. The accuracy of the first and last 12 h in predicting whether the 24-h study was abnormal was 85% and 87%, respectively. The accuracy in predicting whether the ZMD for the 24-h study was abnormal was 73% and 83%, respectively, with an overall 39% false-negative rate. The 12-h study reproducibility was 72% for the total score and 56% for the ZMD. Since the original standards were determined from 18- to 24-h recordings, the test was restandardized based on 12-h recordings from patients with normal 24-h studies. Restandardization did not improve the accuracy or reproducibility. The high false-negative rate for the ZMD and the poor reproducibility cast serious doubt on the utility of 12-h pH recordings, especially in patients with respiratory symptoms. |
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Authors:
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C A Friesen; C Hodge; C C Roberts |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of pediatric gastroenterology and nutrition Volume: 12 ISSN: 0277-2116 ISO Abbreviation: J. Pediatr. Gastroenterol. Nutr. Publication Date: 1991 Feb |
Date Detail:
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Created Date: 1991-07-23 Completed Date: 1991-07-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8211545 Medline TA: J Pediatr Gastroenterol Nutr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 166-8 Citation Subset: IM |
Affiliation:
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Section of Gastroenterology, Children's Mercy Hospital, Kansas City, Missouri 64108. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Child Child, Preschool Esophagus / physiology* Gastroesophageal Reflux / physiopathology Humans Hydrogen-Ion Concentration Infant Infant, Newborn Monitoring, Physiologic Posture / physiology Predictive Value of Tests Reproducibility of Results Sleep / physiology Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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