| Accuracy of the ratio of triglycerides to high-density lipoprotein cholesterol for predicting low-density lipoprotein cholesterol particle sizes, phenotype B, and particle concentrations among Asian Indians. | |
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MedLine Citation:
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PMID: 16563906 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Asian Indians have unusually high rates of coronary artery disease. Small low-density lipoprotein (LDL) particle predominance (phenotype B) is associated with a fourfold atherogenic risk. This study examined the accuracy of a triglyceride/high-density lipoprotein cholesterol (HDL) ratio of > or =3.8 (determined from the Adult Treatment Panel III guidelines, normal triglycerides <150 mg/dl and HDL >40 mg/dl) for predicting phenotype B in Asian Indians. Fasting blood samples were collected from 150 healthy Asian Indians. LDL size analysis was performed by nuclear magnetic resonance spectroscopy. The triglyceride/HDL cholesterol ratio correlated inversely with the LDL size and positively with the particle concentration. A triglyceride/HDL cholesterol ratio of > or =3.8 had 76% sensitivity, 93% specificity, and 83% positive and 89% negative predictive values for predicting phenotype B. |
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Authors:
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Narendra C Bhalodkar; Steve Blum; Enas A Enas |
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Publication Detail:
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Type: Journal Article Date: 2006-02-21 |
Journal Detail:
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Title: The American journal of cardiology Volume: 97 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2006 Apr |
Date Detail:
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Created Date: 2006-03-27 Completed Date: 2006-05-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 1007-9 Citation Subset: AIM; IM |
Affiliation:
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Division of Cardiology, Department of Medicine, Bronx-Lebanon Hospital Center, Albert Einstein College of Medicine, Bronx, New York, USA. nbhalodkar@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Asian Continental Ancestry Group* Cholesterol, HDL / blood* Cholesterol, LDL / blood*, genetics* Female Humans India / ethnology Male Middle Aged Particle Size Phenotype* Predictive Value of Tests Reproducibility of Results Triglycerides / blood* |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Triglycerides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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