| Accuracy of preoperative T-staging of gallbladder carcinoma using MDCT. | |
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MedLine Citation:
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PMID: 18094296 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The objective of our study was to evaluate the performance of MDCT in the preoperative T-staging of gallbladder cancer and to determine whether adding multiplanar reconstruction (MPR) images to axial images can improve the accuracy of MDCT for the T-staging of gallbladder cancer. MATERIALS AND METHODS: Two abdominal radiologists retrospectively reviewed by consensus axial images of portal phase MDCT scans of 118 patients who had pathologically confirmed gallbladder cancers; they then reviewed the axial and MPR images from 53 of the 118 patients who had undergone MPR imaging. Local disease spread was evaluated according to the TNM system, and the results were compared with the pathologic findings using the McNemar test. The MDCT performance to differentiate each T-stage was evaluated using Fisher's exact test. RESULTS: The sensitivities of the ability to differentiate the < or = T1 versus > or = T2 lesions, < or = T2 versus > or = T3 lesions, and < or = T3 versus T4 lesions were 79.3%, 92.7%, and 100%, respectively; the specificities were 98.8%, 86%, and 100%, respectively (p < 0.0001). The overall accuracy for the T-stage was 83.9%. In the 53 patients with MPR images, the combined reading of the axial and MPR images increased the diagnostic accuracy compared with axial image reading only from 71.7% to 84.9%, a statistically significant degree (p = 0.0233). CONCLUSION: MDCT provided 83.9% accuracy in the diagnosis of the local extent of gallbladder carcinomas, thereby showing acceptable sensitivity and specificity. The addition of MPR images to the axial CT data increased the accuracy. |
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Authors:
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Soo Jin Kim; Jeong Min Lee; Jae Young Lee; Jin Young Choi; Se Hyung Kim; Joon Koo Han; Byung Ihn Choi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 190 ISSN: 1546-3141 ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2008 Jan |
Date Detail:
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Created Date: 2007-12-20 Completed Date: 2008-01-14 Revised Date: 2008-02-15 |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
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Languages: eng Pagination: 74-80 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology and Institute of Radiation Medicine, Seoul National University Hospital, 28, Yeongeon-dong, Jongno-gu, Seoul 110-744, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Female Gallbladder Neoplasms / pathology*, radiography* Humans Male Middle Aged Neoplasm Staging Preoperative Care* Radiographic Image Enhancement / methods* Sensitivity and Specificity Tomography, X-Ray Computed |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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