Document Detail

Accuracy of nonstenotic coronary atherosclerosis assessment by multi-detector computed tomography.
MedLine Citation:
PMID:  17526989     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The ability to evaluate coronary stenosis using multi-detector computed tomography (MDCT) has been well discussed. In contrast, several studies demonstrated that the plaque burden measured by intravascular ultrasound (IVUS) has a relationship to the risk of cardiovascular events. the accuracy of MDCT was studied to determine plaque and vessel size compared with IVUS. METHODS AND RESULTS: Fifty-six proximal lesions (American College of Cardiology/American Heart Association classification: segment 1, 5, 6) from 33 patients were assessed using MDCT and IVUS. The plaque and vessel area were measured from the cross-sectional image using both MDCT and IVUS. Eight coronary artery lesions with motion artifacts and heavily calcified plaques were excluded from the analysis. The vessel and lumen size evaluated using MDCT were closely correlated with those evaluated by IVUS (R(2)=0.614, 0.750 respectively). Furthermore, there was a strong correlation between percentage plaque area assessed by MDCT and IVUS (R(2)=0.824). CONCLUSION: MDCT can noninvasively quantify coronary atherosclerotic plaque with good correlation compared with IVUS in patients with atherosclerosis.
Tetsuya Hara; Shinichiro Yamada; Takatoshi Hayashi; Yoshihiro Ikeda; Kohei Yamashiro; Kazuo Mizutani; Sachiyo Iwata; Katsunori Okajima; Yasue Tsukishiro; Kensuke Matsumoto; Takafumi Akagami; Hiroyuki Kumagai; Mitsuo Kinugasa; Michihiko Inoue; Naoki Murai; Ichiro Izawa; Teishi Kajiya
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  71     ISSN:  1346-9843     ISO Abbreviation:  Circ. J.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-05-28     Completed Date:  2007-12-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  911-4     Citation Subset:  IM    
Division of Cardiovascular and Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
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MeSH Terms
Coronary Artery Disease / radiography*,  ultrasonography
Coronary Vessels / ultrasonography
Middle Aged
Predictive Value of Tests
Retrospective Studies
Tomography, X-Ray Computed*
Ultrasonography, Interventional

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