Document Detail


Accuracy of non-invasive ICP assessment can be increased by an initial individual calibration.
MedLine Citation:
PMID:  19388287     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: In a formerly introduced mathematical model, intracranial pressure (ICP) could be non-invasively assessed using cerebral blood flow velocity (FV) and arterial blood pressure (ABP). The current study attempts to check whether the accuracy of the non-invasive ICP assessment (nICP) improves after an initial individual calibration by implanted ICP probes.
METHODS: Thirteen patients with brain lesions (35-77 years, mean: 58 +/- 13 years) were studied. FV, ABP and ICP signals were recorded at days 1, 2, 4 and 7. nICP was calculated and compared to ICP. In the first recording of each patient the (invasively assessed) ICP signal was used to calibrate the nICP calculation procedure, while the follow-up recordings were used for its validation.
FINDINGS: In 11 patients 22 follow-up recordings were performed. The mean deviation between ICP and the original nICP (+/- SD) was 8.3 +/- 7.9 mmHg. Using the calibrated method this deviation was reduced to 6.7 +/- 6.7 mmHg (P < 0.005).
CONCLUSIONS: Initial individual calibration of nICP assessment method significantly improves the accuracy of nICP estimation on subsequent days. This hybrid method of ICP assessment may be used in intensive care units in patients with initially implanted ICP probes. After removal of the probes, ICP monitoring can be continued using the calibrated nICP assessment procedure.
Authors:
B Schmidt; M Weinhold; M Czosnyka; S A May; R Steinmeier; J Klingelhöfer
Related Documents :
2211877 - The time course of intracranial pathophysiological changes following experimental subar...
21525967 - Management of blood pressure in patients with diabetes.
1997507 - The effect of stable xenon on icp.
16703877 - Predictive value of initial computerized tomography scan, intracranial pressure, and st...
6240447 - Reversal of cardiac hypertrophy in humans.
8230857 - Left ventricular ors widening decreases emax without lowering vo2-pva relation in dog h...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurochirurgica. Supplement     Volume:  102     ISSN:  0065-1419     ISO Abbreviation:  Acta Neurochir. Suppl.     Publication Date:  2008  
Date Detail:
Created Date:  2009-04-24     Completed Date:  2009-06-10     Revised Date:  2014-02-19    
Medline Journal Info:
Nlm Unique ID:  100962752     Medline TA:  Acta Neurochir Suppl     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  49-52     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Blood Flow Velocity / physiology
Brain Injuries / physiopathology*
Calibration
Cerebrovascular Circulation*
Female
Follow-Up Studies
Humans
Intracranial Pressure / physiology*
Male
Middle Aged
Models, Cardiovascular
Outcome Assessment (Health Care)
Pattern Recognition, Automated / methods
Ultrasonography, Doppler, Transcranial
Grant Support
ID/Acronym/Agency:
G9439390//Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Generation of very low frequency cerebral blood flow fluctuations in humans.
Next Document:  The impact of ventricular catheter impregnated with antimicrobial agents on infections in patients w...