| Accuracy and limitations of transabdominal fetal echocardiography at 12-15 weeks of gestation in a population at high risk for congenital heart disease. | |
| | |
MedLine Citation:
|
PMID: 11192105 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: Evaluation of transabdominal fetal echocardiography at 12-15 weeks of gestation. DESIGN: Retrospective analysis. SETTING: Tertiary fetal cardiology unit. SAMPLE: Two hundred twenty-nine consecutive fetuses imaged at 12-15 weeks of gestation over a 45-month period. METHODS: Retrospective analysis of echocardiography and autopsy reports. MAIN OUTCOME MEASURES: Accuracy of early echocardiography for the detection of abnormalities of the cardiac connections. RESULTS: Diagnostic images were obtained in 226/229 fetuses (98.7%). Abnormalities of the cardiac connections were detected in 13 fetuses (5.7%) on the initial scan. Where information was available (n = 11), the echocardiographic findings were confirmed at autopsy or postnatally. In two of the 13 cases of congenital heart disease, repeat echocardiography was necessary to provide additional cardiological information. Of the 213 cases in whom a normal initial report was issued, four (1.7%) had congenital heart disease diagnosed later in pregnancy (n = 3) or postnatally (n = 1). Three of these fetuses had haemodynamically insignificant ventricular septal defects and one developed a dilated cardiomyopathy later in gestation. CONCLUSIONS: Transabdominal fetal echocardiography can be performed at 12-15 weeks of gestation permitting accurate early detection of major congenital heart defects in a high risk population. Some forms of congenital heart disease, usually minor, may not be detectable at such an early stage. |
| | |
Authors:
|
J M Simpsom; A Jones; N Callaghan; G K Sharland |
Related Documents
:
|
23453255 - Pregnancy per ai differences between primiparous and multiparous high-yield dairy cows ... 23667735 - Impact of maternal vitamin d status during pregnancy on the prevalence of neonatal vita... 2565825 - Developmental characteristics of fetal arrhythmias during the period from intrauterine ... 19629245 - Congenital heart disease in pregnancy. 15685665 - First-trimester diagnosis of imperforate anus. 9674095 - Fetal hepatosplenomegaly: an isolated sonographic sign of trisomy 21 in a case of myelo... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: BJOG : an international journal of obstetrics and gynaecology Volume: 107 ISSN: 1470-0328 ISO Abbreviation: BJOG Publication Date: 2000 Dec |
Date Detail:
|
Created Date: 2001-01-12 Completed Date: 2001-03-15 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 100935741 Medline TA: BJOG Country: England |
Other Details:
|
Languages: eng Pagination: 1492-7 Citation Subset: AIM; IM |
Affiliation:
|
Department of Congenital Heart Disease, Guy's Hospital, London, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Echocardiography
/
methods,
standards* Female Gestational Age Heart Defects, Congenital / ultrasonography* Humans Pregnancy Retrospective Studies Risk Factors Sensitivity and Specificity Ultrasonography, Prenatal / methods, standards* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Hormonal regulation of neonatal weight: placental leptin and leptin receptors.
Next Document: RhD genotyping by quantitative fluorescent polymerase chain reaction: a new approach.