Document Detail

Accuracy of invasive arterial pressure monitoring in cardiovascular patients: an observational study.
MedLine Citation:
PMID:  25433536     Owner:  NLM     Status:  Publisher    
IntroductionCritically ill patients and patients undergoing high-risk and major surgery, are instrumented with intra-arterial catheters and invasive blood pressure is considered the ¿gold standard¿ for arterial pressure monitoring. Nonetheless, artifacts due to inappropriate dynamic response of the fluid-filled monitoring systems may lead to clinically relevant differences between actual and displayed pressure values. We sought to analyze the incidence and causes of resonance/underdamping phenomena in patients undergoing major vascular and cardiac surgery.MethodsArterial pressures were measured invasively and, according to the fast-flush Gardner¿s test, each patient was attributed to one of two groups depending on the presence (R-group) or absence (NR-group) of resonance/underdamping. Invasive pressure values were then compared with the non-invasive ones.ResultsA total of 11,610 pulses and 1,200 non-invasive blood pressure measurements were analyzed in 300 patients. Ninety-two out of 300 (30.7%) underdamping/resonance arterial signals were found. In these cases (R-group) systolic invasive blood pressure (IBP) average overestimation of non-invasive blood pressure (NIBP) was 28.5 (15.9) mmHg (P <0.0001) while in the NR-group the overestimation was 4.1(5.3) mmHg (P <0.0001). The mean IBP-NIBP difference in diastolic pressure in the R-group was ¿2.2 (10.6) mmHg and, in the NR-group ¿1.1 (5.8) mmHg. The mean arterial pressure difference was 7.4 (11.2) mmHg in the R-group and 2.3 (6.4) mmHg in the NR-group. A multivariate logistic regression identified five parameters independently associated with underdamping/resonance: polydistrectual arteriopathy (P =0.0023; OR¿=¿2.82), history of arterial hypertension (P =0.0214), chronic obstructive pulmonary disease (P =0.198; OR¿=¿2.09), arterial catheter diameter (20 vs. 18 gauge) (P <0.0001; OR¿=¿0.34) and sedation (P =0.0131; OR¿=¿0.5). The ROC curve for the maximal pressure¿time ratio, showed an optimum selected cut-off point of 1.67 mmHg/msec with a specificity of 97% (95% CI: 95.13 to 99.47%) and a sensitivity of 77% (95% CI: 67.25 to 85.28%) and an area under the ROC curve by extended trapezoidal rule of 0.88.ConclusionPhysicians should be aware of the possibility that IBP can be inaccurate in a consistent number of patients due to underdamping/resonance phenomena. NIBP measurement may help to confirm/exclude the presence of this artifact avoiding inappropriate treatments.
Stefano Romagnoli; Zaccaria Ricci; Diego Quattrone; Lorenzo Tofani; Omar Tujjar; Gianluca Villa; Salvatore M Romano; A De Gaudio
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-11-30
Journal Detail:
Title:  Critical care (London, England)     Volume:  18     ISSN:  1466-609X     ISO Abbreviation:  Crit Care     Publication Date:  2014 Nov 
Date Detail:
Created Date:  2014-11-30     Completed Date:  -     Revised Date:  2014-12-1    
Medline Journal Info:
Nlm Unique ID:  9801902     Medline TA:  Crit Care     Country:  -    
Other Details:
Languages:  ENG     Pagination:  644     Citation Subset:  -    
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