Document Detail

Accuracy in gamma camera measurements of point source velocities.
MedLine Citation:
PMID:  10894565     Owner:  NLM     Status:  MEDLINE    
Mucociliary clearance is impaired in many diseases of the respiratory system. We have developed a method for measuring tracheal mucus velocity by the dynamic study of a single point source of radioactivity deposited in the trachea by cricothyroid injection. Preliminary results suggest that patients with airways disease have very low tracheal mucus velocities (<2 mm x min(-1)). The aim of this experiment was to explore the ability of current scintillation detection systems to track a single point as it moves in a dynamic study in small increments and at low velocity (movements of the order of 1 mm). Background noise was estimated to contribute an error in positioning of 0.16 mm (1 standard deviation). Overall errors in velocity were estimated at 0.2 mm x min(-1). This suggests that standard instrumentation in use in most nuclear medicine departments has the capacity to measure accurately velocities as low as 1 mm x min(-1).
L C Morgan; M A Pearson; D W Mackey; J Rutland; R U de Iongh; M J Peters; H van der Wall
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Nuclear medicine communications     Volume:  21     ISSN:  0143-3636     ISO Abbreviation:  Nucl Med Commun     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-11-21     Completed Date:  2000-11-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8201017     Medline TA:  Nucl Med Commun     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  553-6     Citation Subset:  IM    
Department of Respiratory Medicine, Concord Repatriation General Hospital, NSW, Australia.
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MeSH Terms
Gamma Cameras*
Mucociliary Clearance*
Radionuclide Imaging / instrumentation,  methods
Reproducibility of Results
Respiratory Tract Diseases / physiopathology*,  radionuclide imaging*
Trachea / radionuclide imaging

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