| Accuracy and feasibility of a simplified approach to assess the regurgitant orifice area in patients with mitral regurgitation. | |
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MedLine Citation:
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PMID: 15068139 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Regurgitant orifice area (ROA) has been proposed as a marker of severity in patients with mitral regurgitation (MR). However, such fundamental quantitative echocardiographic parameter has failed to achieve widespread use, since it is difficult to measure. In the present study, we evaluated the accuracy and feasibility of a simplified method for quantification of ROA in patients with varying grades of MR. METHODS: We studied two groups of individuals with echocardiographically diagnosed MR. Group I included 70 patients retrospectively evaluated, in whom we were able to obtain an adequate flow convergence region by color Doppler and recording of continuous-wave Doppler regurgitant jet. Group II included 32 MR patients prospectively evaluated. The degee of MR was assessed by two quantitative echocardiographic measures: the regurgitant fraction and the ROA, calculated either dividing peak flow rate by the maximal velocity through the orifice or with the simplified formula: r2/2. RESULTS: In group I, the mechanism of MR was organic in 18 patients and ischemic/functional in 52 patients. ROA calculated by the simplified formula correlated well with the conventional one (r = 0.85) and with the regurgitant fraction (r = 0.72). In group II, we could calculate the ROA by the conventional method in 56% of patients, whereas use of the simplified approach allowed ROA evaluation in 78% of patients. CONCLUSION: Our data suggest that the use of a simplified formula may increase the number of patients having ROA, a fundamental parameter of MR severity, measured in clinical practice. |
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Authors:
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Luigi Ascione; Mario De Michele; Maria Accadia; Salvatore Rumolo; Lucia Damiano; Pasquale Guarini; Antonello D'Andrea; Bernardino Tuccillo |
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Publication Detail:
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Type: Comparative Study; Evaluation Studies; Journal Article |
Journal Detail:
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Title: The international journal of cardiovascular imaging Volume: 20 ISSN: 1569-5794 ISO Abbreviation: Int J Cardiovasc Imaging Publication Date: 2004 Apr |
Date Detail:
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Created Date: 2004-04-07 Completed Date: 2004-11-06 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100969716 Medline TA: Int J Cardiovasc Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 95-100 Citation Subset: IM |
Affiliation:
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Division of Cardiology, S. Maria di Loreto Hospital, Naples, Italy. luigi.ascione20@tin.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Blood Flow Velocity / physiology Cardiomyopathy, Dilated / ultrasonography Child Coronary Artery Disease / ultrasonography Coronary Circulation / physiology Echocardiography, Doppler, Color Feasibility Studies Humans Image Enhancement Italy Middle Aged Mitral Valve Insufficiency / diagnosis*, etiology Retrospective Studies Rheumatic Heart Disease / ultrasonography Severity of Illness Index Statistics as Topic |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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