Document Detail


Accuracy of computed tomographic intravenous cholangiography (CT-IVC) with iotroxate in the detection of choledocholithiasis.
MedLine Citation:
PMID:  15627178     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To determine the accuracy of computed tomographic intravenous cholangiography (CT-IVC) for detection of choledocholithiasis. Sixty-five patients undergoing endoscopic retrograde cholangiography (ERC) underwent CT-IVC prior to ERC, using a single detector helical CT following intravenous infusion of 100 ml iotroxate. Patients with bilirubin levels >3 times normal were excluded. ERC was indeterminate in three patients (4.7%) and CT-IVC in four (6.3%). Twenty-three patients had ductal calculi at ERC, and CT-IVC was positive in 22, with two false positives and one false negative: sensitivity 95.6%, specificity 94.3%. Stones were multiple in nine and solitary in 14. Of the 14 solitary stones, ten were <or=5 mm and eight were <or=4 mm. The bilirubin level in positive cases was within normal in 20. Maximum intensity projection (MIP) reformats showed stones in only 27% of cases and surface rendered (SR) reformats in none. CT-IVC is highly accurate for detection of ductal calculi, including single small calculi, with a normal or near normal serum bilirubin. Axial images should be used for interpretation rather than MIP or SR reformats.
Authors:
Robert N Gibson; Janette M Vincent; Tony Speer; Neil A Collier; Keith Noack
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2004-12-31
Journal Detail:
Title:  European radiology     Volume:  15     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-07-21     Completed Date:  2006-08-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1634-42     Citation Subset:  IM    
Affiliation:
Department of Radiology, Royal Melbourne Hospital, University of Melbourne, Mebourne, Victoria, 3050, Australia. r.gibson@unimelb.edu.au
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MeSH Terms
Descriptor/Qualifier:
Bilirubin / blood
Cholangiography* / methods
Cholangiopancreatography, Endoscopic Retrograde
Choledocholithiasis / radiography*
Contrast Media
Female
Humans
Iodipamide / analogs & derivatives,  diagnostic use
Male
Middle Aged
Prospective Studies
Tomography, X-Ray Computed* / methods
Chemical
Reg. No./Substance:
0/Contrast Media; 606-17-7/Iodipamide; 635-65-4/Bilirubin; 68890-05-1/iotroxamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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