| Accuracy of breath-hold magnetic resonance imaging in preoperative staging of organ-confined renal cell carcinoma. | |
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MedLine Citation:
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PMID: 15100535 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To determine the accuracy of breath-hold magnetic resonance (MR) imaging for preoperative staging of patients with organ-confined (stage I) renal cell carcinoma. MATERIALS AND METHODS: Preoperative MR examinations of 43 patients (50 lesions) who underwent nephrectomy were reviewed. The MR examination consisted entirely of breath-hold sequences, and images were retrospectively evaluated by 2 blinded radiologists. Reviewers independently evaluated each case for findings that could affect the radiologic staging, particularly those that distinguish between organ-confined (stage I) and non-organ-confined (>stage II) disease. Each reviewer assigned a stage, and results were correlated with findings at surgery and pathologic examination. RESULTS: The difference between both reviewers and pathologic findings in evaluating an intact renal capsule (stage I) was statistically significant (P < 0.05) and resulted in a statistically significant difference between radiologic and pathologic staging (Wilcoxon test, P < 0.05). The kappa test demonstrated moderate agreement between radiologic and pathologic staging (82% and 80% for reviewers 1 and 2, kappa = 0.54 and 0.80, respectively) and substantial agreement (90%, kappa = 0.80) between the 2 reviewers in assigning a radiologic stage. CONCLUSION: Breath-hold MR imaging has an accuracy ranging between 80% and 82% in staging patients with organ-confined renal cell carcinoma, with substantial (90%) agreement between readers. |
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Authors:
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Ihab R Kamel; Mary G Hochman; Mary T Keogan; John Eng; Harold E Longmaid; William DeWolf; Robert R Edelman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of computer assisted tomography Volume: 28 ISSN: 0363-8715 ISO Abbreviation: J Comput Assist Tomogr Publication Date: 2004 May-Jun |
Date Detail:
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Created Date: 2004-04-21 Completed Date: 2004-06-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7703942 Medline TA: J Comput Assist Tomogr Country: United States |
Other Details:
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Languages: eng Pagination: 327-32 Citation Subset: IM |
Affiliation:
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The Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. ikamel@jhmi.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Carcinoma, Renal Cell / pathology*, surgery Female Humans Kidney Neoplasms / pathology*, surgery Magnetic Resonance Imaging / methods* Male Middle Aged Neoplasm Staging Preoperative Care Reproducibility of Results Respiration Retrospective Studies Single-Blind Method |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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