Document Detail

Accuracy of Regional Cerebral Oxygen Saturation in Predicting Postoperative Cognitive Dysfunction After Total Hip Arthroplasty: Regional Cerebral Oxygen Saturation Predicts POCD.
MedLine Citation:
PMID:  23151365     Owner:  NLM     Status:  Publisher    
To estimate the accuracy of regional cerebral oxygen saturation (rSO(2)) in predicting postoperative cognitive dysfunction (POCD) for patients undergoing total hip arthroplasty, 46 patients aged more than 50years old were enrolled. We measured the patients' cognitive function by using a battery of six neuropsychological tests before surgery and then 7days after surgery again. rSO(2) was continuously monitored by near-infrared spectroscopy during surgery. POCD was present in 9 (19.6%) patients 1week after surgery. Logistic regression analysis showed that increasing age [OR=1.224, P=0.035] and maximum percentage drop in rSO(2) (rSO(2%max)) [OR=1.618, P=0.011] were significant risk factors for POCD. The area under the receiver operating characteristic curve of rSO(2%max) was 0.833 [95% confidence interval (CI) 0.615-1.051] at cutoff value of 11%. The specificity and sensitivity of rSO(2%max) >11% in predicting POCD were 77.8% and 86.5%, respectively. rSO(2%max) more than 11% was a potential predictor for POCD.
Rong Lin; Fujun Zhang; Qingsheng Xue; Buwei Yu
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-11
Journal Detail:
Title:  The Journal of arthroplasty     Volume:  -     ISSN:  1532-8406     ISO Abbreviation:  J Arthroplasty     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8703515     Medline TA:  J Arthroplasty     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Department of Anesthesiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P. R. China.
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