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Accuracy of multidetector CT scans in staging of renal carcinoma.
MedLine Citation:
PMID:  20937417     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: The aim of this study is to determine the diagnostic accuracy of multidetector-row computed tomography (MDCT) compared to histopathological findings in tumor staging of renal cell carcinoma, with the focus on tumor size and stage, renal vein involvement, and peri-renal infiltration.
MATERIALS AND METHODS: In a retrospective study, a total of 98 consecutive patients with renal cell carcinoma were preoperatively assessed for tumor staging using multidetector-row CT. Triphasic CT imaging (i.e., noncontrast, arterial, and parenchymal phase) was performed using multidetector-row CT with the slice thickness of 5 mm and using multi planar reconstructions to define the tumor characteristics. A single blinded reader evaluated the CT scans independently who reviewed the scan on multi planar reconstructions. The results were then correlated with the histopathological results.
RESULTS: A total of 98 renal cell carcinomas were proven on histopathology. There was a significant (p 0.05) difference in the mean maximum radiological and maximum pathological diameter of the tumor with radiological diameter being greater. Twenty seven tumors were down staged and only 1 was up staged. The specificity of CT for capsular invasion, nodal disease and adrenal involvement was 85, 82 and 98% respectively. The specificity was over 97% for tumor thrombus in renal vein and IVC.
CONCLUSIONS: The multi planar reconstruction capability of multidetector-row CT allowed good specificity in predicting renal vein, IVC involvement, capsular invasion and nodal disease.
Authors:
Syed M Nazim; M Hammad Ather; Kamran Hafeez; Basit Salam
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Publication Detail:
Type:  Journal Article     Date:  2010-10-13
Journal Detail:
Title:  International journal of surgery (London, England)     Volume:  9     ISSN:  1743-9159     ISO Abbreviation:  Int J Surg     Publication Date:  2011  
Date Detail:
Created Date:  2011-01-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101228232     Medline TA:  Int J Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  86-90     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Department of Surgery and Radiology, Aga Khan University, Pakistan.
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