Document Detail

Accumulation and perchlorate exposure potential of lettuce produced in the Lower Colorado River region.
MedLine Citation:
PMID:  15969537     Owner:  NLM     Status:  MEDLINE    
The Colorado River is contaminated with perchlorate concentrations of 1.5-8 microg/L, an anion linked to thyroid dysfunction. Over 90% of the lettuce (Lactuca sativa L.) consumed during the winter months in the United States is produced in the Lower Colorado River region. Studies were conducted in this region to survey the potential for lettuce perchlorate accumulation and estimate potential human exposure to perchlorate from lettuce. Total uptake of perchlorate in the above-ground plant of iceberg lettuce was approximately 5 g/ha. Exposure estimates ranged from 0.45 to 1.8 microg/day depending on lettuce types and trimming. For all lettuce types, hypothetical exposures were less than 4% of the reference dose recommended by the National Academy of Sciences. Results show the relative iodide uptake inhibition potential because of lettuce nitrate was 2 orders of magnitude greater than that associated with the corresponding trace levels of perchlorate. These data support the conclusion that potential perchlorate exposures from lettuce irrigated with Colorado River water are negligible relative to acute or long-term harmful amounts.
C A Sanchez; R I Krieger; N Khandaker; R C Moore; K C Holts; L L Neidel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  53     ISSN:  0021-8561     ISO Abbreviation:  J. Agric. Food Chem.     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-06-22     Completed Date:  2005-08-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5479-86     Citation Subset:  IM    
Department of Soil, Water, and Environmental Sciences, Yuma Agricultural Center, The University of Arizona, 85364, USA.
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MeSH Terms
Lettuce / chemistry*,  growth & development*,  metabolism
Nitrates / analysis
Perchloric Acid / analysis*,  metabolism
Water Pollutants / analysis
Reg. No./Substance:
0/Nitrates; 0/Water Pollutants; 0/perchlorate; 7601-90-3/Perchloric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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