Document Detail


ACCUMULATION OF INORGANIC POLYPHOSPHATE IN AEROBACTER AEROGENES. I. RELATIONSHIP TO GROWTH AND NUCLEIC ACID SYNTHESIS.
MedLine Citation:
PMID:  14058944     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Harold, F. M. (National Jewish Hospital, Denver, Colo.). Accumulation of inorganic polyphosphate in Aerobacter aerogenes. I. Relationship to growth and nucleic acid synthesis. J. Bacteriol. 86:216-221. 1963.-Growing cells of Aerobacter aerogenes contain traces of inorganic polyphosphate, but large amounts often accumulate when growth ceases as the result of a nutritional deficiency. The reciprocal relationship between growth and polyphosphate accumulation was traced to competition between nucleic acid synthesis and polyphosphate for intracellular phosphorus. Polyphosphate accumulated only after nucleic acid synthesis had ceased. Resumption of nucleic acid synthesis (with or without concurrent cell growth) induced rapid degradation of the polyphosphate with transfer of the phosphorus to ribonucleic acid (RNA). At the same time, incorporation of P(32) into polyphosphate was reduced, though not abolished. Competition for adenosine triphosphate may be part of the explanation. In addition, it appears that polyphosphate degradation is accelerated under conditions which permit rapid nucleic acid synthesis, the phosphorus released being trapped in RNA.
Authors:
F M HAROLD
Related Documents :
15422114 - Free amino acids and nucleic acid content of cell nuclei isolated by a modification of ...
1090594 - Utilization of nucleoside monophosphates per se for intraperiplasmic growth of bdellovi...
22006384 - Graphene and graphene oxide: two ideal choices for the enrichment and ionization of lon...
1258094 - Microspectrophotometric quantitation of nucleic acid and protein in irradiated epidermis.
18074224 - Concise chemical synthesis of a tetrasaccharide repeating unit of the o-antigen of hafn...
24813434 - Preventive effect of α-lipoic acid on prepulse inhibition deficits in a juvenile two-h...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of bacteriology     Volume:  86     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  1963 Aug 
Date Detail:
Created Date:  1964-02-01     Completed Date:  1996-12-01     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  216-21     Citation Subset:  OM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
DNA, Bacterial*
Enterobacter aerogenes*
Metabolism*
Phosphates*
Phosphorus Isotopes*
RNA, Bacterial*
Radiometry*
Research*
Chemical
Reg. No./Substance:
0/DNA, Bacterial; 0/Phosphates; 0/Phosphorus Isotopes; 0/RNA, Bacterial
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  EFFECT OF HUMAN SERUM ON FATALITY OF STAPHYLOCOCCAL INFECTION IN MICE.
Next Document:  ACCUMULATION OF INORGANIC POLYPHOSPHATE IN AEROBACTER AEROGENES. II. ENVIRONMENTAL CONTROL AND THE R...