Document Detail

Accumulation of foreign gases during closed-system anaesthesia.
MedLine Citation:
PMID:  8688267     Owner:  NLM     Status:  MEDLINE    
In a previous study, accumulation of methane was found at the end of closed-system ventilation. As on-line analysis of gas concentrations is now available, we examined the progressive increase in concentrations of methane, carbon monoxide and acetone during modern, closed-system conditions, and their influence on infrared halothane analysis, in 26 non-pregnant, gynaecological patients. A computer-controlled closed-system anaesthesia apparatus (PhysioFlex) was used for ventilation during total i.v. anaesthesia (excluding nitrous oxide or potent inhalation anaesthetics) for gynaecological laparoscopy. Methane, carbon monoxide and acetone concentrations were analysed every 15 min in a photoacoustic infrared monitor and halothane concentrations by built-in infrared spectrometry. Mean methane concentrations increased progressively after 105 min to 941 (SD 1094) ppm, but concentrations of carbon monoxide and acetone did not increase significantly. In 18 patients, the infrared measurement falsely indicated 0.79 (0.52)% "halothane" after 60 min, but no reading appeared in the other eight patients. We conclude that methane accumulated progressively under strict closed-system conditions in higher concentrations than reported previously. In two-thirds of patients it induced false "halothane" readings.
L Versichelen; G Rolly; H Vermeulen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  76     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1996 May 
Date Detail:
Created Date:  1996-08-26     Completed Date:  1996-08-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  668-72     Citation Subset:  IM    
Department of Anaesthesia, University Hospital, Ghent, Belgium.
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MeSH Terms
Acetone / analysis*
Anesthesia, Closed-Circuit* / instrumentation
Anesthesia, Intravenous
Carbon Monoxide / analysis*
Equipment Design
Halothane / analysis
Methane / analysis*
Middle Aged
Time Factors
Reg. No./Substance:
151-67-7/Halothane; 630-08-0/Carbon Monoxide; 67-64-1/Acetone; 74-82-8/Methane

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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