| Accumulation of excess visceral fat is a risk factor for pancreatic fistula formation after total gastrectomy. | |
| | |
MedLine Citation:
|
PMID: 19267237 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The effect of obesity on gastrectomy in patients with gastric cancer is controversial. The degree of abdominal fat increases the technical difficulty of abdominal surgery. This study examined the effect of visceral fat on total gastrectomy and risk factors associated with the formation of pancreatic fistula. METHODS: Between February 2001 and April 2007, 191 patients with gastric cancer underwent total gastrectomy. The visceral fat area (VFA) was calculated from computed tomography (CT) scans taken at the level of the umbilicus using FatScan Software. Patients were divided into high- (> or =100 cm(2), n = 52) and low-VFA groups (<100 cm(2), n = 139), and also into high- (> or =25 kg/m(2), n = 47) and low-BMI groups (<25 kg/m(2), n = 144). RESULTS: Blood loss and incidence of pancreatic fistula were significantly higher in the high- than low-VFA group. However, only blood loss was significantly different between the high- and low-BMI groups. VFA, blood loss, and splenectomy were identified as significant risk factors for pancreatic fistula formation on univariate analysis, and multivariate logistic regression analysis of these factors identified VFA (p = 0.0001) and splenectomy (p = 0.0014) as significant predictors of pancreatic fistula. CONCLUSIONS: VFA is a better indicator for pancreatic fistula formation after total gastrectomy than is BMI. Lymph node dissection must be performed carefully, especially in patients with visceral fat accumulation during total gastrectomy with splenectomy. |
| | |
Authors:
|
Koji Tanaka; Isao Miyashiro; Masahiko Yano; Kentaro Kishi; Masaaki Motoori; Yousuke Seki; Shingo Noura; Masayuki Ohue; Terumasa Yamada; Hiroaki Ohigashi; Osamu Ishikawa |
Related Documents
:
|
929107 - Changes in pancreatic and intestinal enzyme activities following chenodeoxycholic acid ... 21094757 - Dietary sodium butyrate supplementation increases digestibility and pancreatic secretio... 2045817 - Antihyperlipidemic effect of flavonoids from prunus davidiana. 1886947 - Interaction of msg taste with nutrition: perspectives in consummatory behavior and dige... 22039787 - Pharmacokinetic features of the antiparasitic macrocyclic lactones. 22062867 - The effects of carrageenan and pectin on some quality characteristics of low-fat beef f... |
Publication Detail:
|
Type: Journal Article Date: 2009-03-08 |
Journal Detail:
|
Title: Annals of surgical oncology Volume: 16 ISSN: 1534-4681 ISO Abbreviation: Ann. Surg. Oncol. Publication Date: 2009 Jun |
Date Detail:
|
Created Date: 2009-05-05 Completed Date: 2009-06-18 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9420840 Medline TA: Ann Surg Oncol Country: United States |
Other Details:
|
Languages: eng Pagination: 1520-5 Citation Subset: IM |
Affiliation:
|
Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Japan. tanaka-ko@mc.pref.osaka.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Female Gastrectomy / adverse effects* Humans Intra-Abdominal Fat* Lymph Node Excision / adverse effects* Male Middle Aged Obesity / complications* Pancreatic Fistula / etiology* Risk Factors Stomach Neoplasms / complications, surgery* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Identification and antifungal assay of a wheat beta-1,3-glucanase.
Next Document: A novel approach for the detection of DNA using immobilized peptide nucleic acid (PNA) probes and si...