| Acclimatization at high altitude in gradual and acute induction. | |
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MedLine Citation:
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PMID: 7592207 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The study assessed physiological responses to induction to high altitude first to 3,500 m and then to 4,200 m and compared the time course of altitude acclimatization in two groups of male volunteers. The acutely inducted group was transported by aircraft (AI) to 3,500 m in 1 h, whereas the gradually inducted group was transported by road (RI) in 4 days. Baseline recordings of basal cardiovascular, respiratory, and blood gas variables were monitored at sea level as well as at 3,500 m on days 1, 3, 5, and 7. Blood gases were measured on day 10 also. After 15 days at 3,500 m, the subjects were inducted to 4,200 m by road, and measurements were repeated on days 1, 3, and 5, except blood gas variables, which were done on day 10 only. Acute mountain sickness symptoms were recorded throughout. The responses of RI were stable by day 3 of induction at 3,500 m, whereas it took 5 days for AI. Four days in transit for RI appear equivalent to 2 days at 3,500 m for AI. Acclimatization schedules of 3 and 5 days, respectively, for RI and AI are essential to avoid malacclimatization and/or high-altitude illness. Both groups took 3 days at 4,200 m to attain stability for achieving acclimatization. |
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Authors:
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S S Purkayastha; U S Ray; B S Arora; P C Chhabra; L Thakur; P Bandopadhyay; W Selvamurthy |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of applied physiology (Bethesda, Md. : 1985) Volume: 79 ISSN: 8750-7587 ISO Abbreviation: J. Appl. Physiol. Publication Date: 1995 Aug |
Date Detail:
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Created Date: 1995-12-18 Completed Date: 1995-12-18 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8502536 Medline TA: J Appl Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 487-92 Citation Subset: IM; S |
Affiliation:
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Defence Institute of Physiology and Allied Sciences, Timarpur, Delhi, India. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acclimatization
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physiology* Adult Altitude* Altitude Sickness / physiopathology Blood Gas Analysis Body Temperature / physiology Hemodynamics / physiology Humans Male Oxygen Consumption / physiology Respiratory Function Tests Time Factors |
| Comments/Corrections | |
Comment In:
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J Appl Physiol. 1996 Aug;81(2):1035-6
[PMID:
8872678
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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