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Accidental phosgene gas exposure: A review with background study of 10 cases.
MedLine Citation:
PMID:  24339660     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Here, authors present a review on clinical presentation and management of exposure of phosgene gas after reviewing the literature by searching with keywords phosgene exposure on Google, Cochrane, Embase and PubMed with a background of experience gained from 10 patients who were admitted to our institute after an accidental phosgene exposure in February 2011 nearby a city in India. Phosgene is a highly toxic gas, occupational workers may have accidental exposure. The gas can also be generated inadvertently during fire involving plastics and other chemicals and solvents containing chlorine, which is of concern to emergency responders. Phosgene inhalation may cause initially symptoms of respiratory tract irritation, patients feel fine thereafter, and then die of choking a day later because of build up of fluid in the lungs (delayed onset non-cardiogenic pulmonary edema). Phosgene exposure is associated with significant morbidity and mortality. Patients with a history of exposure should be admitted to the hospital for a minimum of 24 h for observation because of the potential for delayed onset respiratory failure and acute respiratory distress syndrome.
Authors:
Arvind Kumar Vaish; Shuchi Consul; Avinash Agrawal; Shyam Chand Chaudhary; Manish Gutch; Nirdesh Jain; Mohit Mohan Singh
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of emergencies, trauma, and shock     Volume:  6     ISSN:  0974-2700     ISO Abbreviation:  J Emerg Trauma Shock     Publication Date:  2013 Oct 
Date Detail:
Created Date:  2013-12-16     Completed Date:  2014-06-24     Revised Date:  2014-06-24    
Medline Journal Info:
Nlm Unique ID:  101493921     Medline TA:  J Emerg Trauma Shock     Country:  India    
Other Details:
Languages:  eng     Pagination:  271-5     Citation Subset:  -    
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