| Accidental intraventricular vincristine administration: an avoidable iatrogenic death. | |
| | |
MedLine Citation:
|
PMID: 8918096 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A patient with acute lymphoblastic leukaemia was mistakenly given vincristine intraventricularly, as part of an intensified course of chemotherapy. Despite a CNS washout and supportive treatment, the patient developed progressive ascending paralysis, gradually lapsed into coma and died some 10 days later. Autopsy and post-mortem histological examination showed evidence of brain death caused by florid encephalomyelitis, apparently induced by the intraventricular administration of vincristine. |
| | |
Authors:
|
G Lau |
Related Documents
:
|
16192726 - Alzheimer's disease: role of size and location of white matter changes in determining c... 11726726 - Early increases in brain myo-inositol measured by proton magnetic resonance spectroscop... 20815706 - Intracranial volume and whole brain volume in infants with unicoronal craniosynostosis. 12575756 - Hypothalamic imprinting by gonadal steroid hormones. 8425036 - Perinatal mortality and intrauterine growth retardation. 3346786 - Decreased early diastolic function after indomethacin administration in premature infants. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Medicine, science, and the law Volume: 36 ISSN: 0025-8024 ISO Abbreviation: Med Sci Law Publication Date: 1996 Jul |
Date Detail:
|
Created Date: 1997-01-02 Completed Date: 1997-01-02 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0400721 Medline TA: Med Sci Law Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 263-5 Citation Subset: IM |
Affiliation:
|
Department of Forensic Medicine, Institute of Science and Forensic Medicine, Singapore, Republic of Singapore. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Antineoplastic Agents, Phytogenic / administration & dosage, poisoning* Fatal Outcome Female Humans Injections, Intraventricular / adverse effects Leukemia, Lymphoid / drug therapy* Medication Errors* Vincristine / administration & dosage, poisoning* |
| Chemical | |
Reg. No./Substance:
|
0/Antineoplastic Agents, Phytogenic; 57-22-7/Vincristine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A survey of male homicide cases resident in an English special hospital.
Next Document: Homicide by strychnine poisoning.