Document Detail


Acceptability of five nonoxynol-9 spermicides.
MedLine Citation:
PMID:  15914133     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To examine the acceptability of five nonoxynol-9 (N-9) spermicides. METHODS: We analyzed data from a randomized trial of five products, including three gels containing different amounts of N-9 per dose, a film and a suppository. In the trial, 1536 participants were asked to use the assigned spermicide for 7 months and to complete questionnaires 4 weeks after admission and at discontinuation. RESULTS: Overall, 43% of participants liked their spermicide "very much." This proportion was higher in the three gel groups than in the suppository and film groups. Difficulty with insertion, messiness and discontent with timing of insertion were common complaints in all groups. After adjustment for selected baseline factors, acceptability on the first questionnaire was not related to duration or consistency of subsequent spermicide use or to subsequent time to pregnancy. CONCLUSIONS: In this study, all five spermicides were considered acceptable by most users. Acceptability did not appear to influence spermicide use or pregnancy risk.
Authors:
Elizabeth G Raymond; Pai Lien Chen; Sean Condon; Joanne Luoto; Kurt T Barnhart; Mitchell D Creinin; Alfred Poindexter; Livia Wan; Mark Martens; Robert Schenken; Richard Blackwell
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Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Contraception     Volume:  71     ISSN:  0010-7824     ISO Abbreviation:  Contraception     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-05-25     Completed Date:  2006-01-10     Revised Date:  2010-09-20    
Medline Journal Info:
Nlm Unique ID:  0234361     Medline TA:  Contraception     Country:  United States    
Other Details:
Languages:  eng     Pagination:  438-42     Citation Subset:  IM    
Affiliation:
Family Health International, PO Box 13950, Research Triangle Park, NC 27709, USA. eraymond@fhi.org
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Gels / administration & dosage
Humans
Nonoxynol / administration & dosage*
Patient Satisfaction
Questionnaires
Spermatocidal Agents / administration & dosage
Suppositories / administration & dosage
Treatment Outcome
United States
Vaginal Creams, Foams, and Jellies / administration & dosage
Grant Support
ID/Acronym/Agency:
M01 RR000056-390785/RR/NCRR NIH HHS; M01 RR000056-400785/RR/NCRR NIH HHS; M01 RR000056-41S20785/RR/NCRR NIH HHS; N01-HD-7-3271./HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
0/Gels; 0/Spermatocidal Agents; 0/Suppositories; 0/Vaginal Creams, Foams, and Jellies; 26027-38-3/Nonoxynol
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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