| Acceptability by rats of aqueous solutions of amino acid analogues. | |
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MedLine Citation:
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PMID: 3432318 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Preferences differed widely when rats were offered choices between water and solutions of various natural amino acids and structurally related analogues. They avoided the branched-chain amino acid valine but preferred solutions of its isomer norvaline and of norleucine. The hydrochloride forms of ornithine and arginine were preferred to water at concentrations up to about 100 mM and avoided at 410 mM; homoarginine.HCl was never preferred and was avoided at 39 and 78 mM. Rats were indifferent to taurine and beta-alanine at most concentrations but refused these amino acids at high concentrations (205 and 410 mM, respectively). In conjunction with earlier observations on feeding behavior in response to dietary additions of amino acids, the results show that selections by rats between water and amino acid solutions cannot be used to predict choices among amino acid-containing diets. |
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Authors:
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J K Tews; J J Repa; A E Harper |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Pharmacology, biochemistry, and behavior Volume: 28 ISSN: 0091-3057 ISO Abbreviation: Pharmacol. Biochem. Behav. Publication Date: 1987 Dec |
Date Detail:
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Created Date: 1988-03-10 Completed Date: 1988-03-10 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0367050 Medline TA: Pharmacol Biochem Behav Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 525-8 Citation Subset: IM |
Affiliation:
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Department of Biochemistry, University of Wisconsin-Madison 53706-1569. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
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pharmacology* Animals Diet Male Rats Rats, Inbred Strains Solutions |
| Grant Support | |
ID/Acronym/Agency:
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AM-10747/AM/NIADDK NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Solutions |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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