| Accelerated utilization of lactate under the effect of hypoxen after intensive exercise. | |
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MedLine Citation:
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PMID: 19023968 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Administration of substrates of energy metabolism in combination with hypoxen (sulfur-containing oligoquinone) promoted the increase in blood lactate concentration during maximum exercise, accelerated lactate utilization, and reduced the lactate/pyruvate ratio during recovery. The in vivo effects are in line with hypoxen capacity to accelerate in vitro oxidation of exogenous NADH in mitochondria by the non-rotenone-dependent pathway realized with participation of cytochrome C. |
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Authors:
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E V Grishina; Ya V Khaustova; V G Pogorelova; A G Pogorelov; M K Kuz'mich; E I Maevskii |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Bulletin of experimental biology and medicine Volume: 145 ISSN: 0007-4888 ISO Abbreviation: Bull. Exp. Biol. Med. Publication Date: 2008 Feb |
Date Detail:
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Created Date: 2008-11-21 Completed Date: 2008-12-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372557 Medline TA: Bull Exp Biol Med Country: United States |
Other Details:
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Languages: eng Pagination: 198-201 Citation Subset: IM |
Affiliation:
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Laboratory of Biosystems Thermodynamics and Energy, Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino. grishina_lena@rambler.ru |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Energy Metabolism Lactates / metabolism* Male Mice Mitochondria, Liver / metabolism NAD / metabolism Oxidation-Reduction Oxygen Consumption Phenyl Ethers / metabolism* Physical Conditioning, Animal* Pyruvic Acid / metabolism Rats Rats, Wistar |
| Chemical | |
Reg. No./Substance:
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0/Lactates; 0/Phenyl Ethers; 127-17-3/Pyruvic Acid; 148465-31-0/olifen; 53-84-9/NAD |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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