Document Detail


Accelerated hypertension--patterns of mortality and clinical factors affecting outcome in treated patients.
MedLine Citation:
PMID:  8210306     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We evaluated the outcome of patients presenting with accelerated hypertension, as part of an audit of the Aberdeen Hypertension Clinic database. Of 3928 patients (2005 male, 1923 female) referred for assessment of hypertension, 128 (77 male, 51 female) presented with accelerated hypertension. The main outcome measures were systolic and diastolic pressure, length of time from referral to death or censor date, and cause of death. Accelerated hypertensives had a higher death rate than other hypertensives. Using life-table analysis, age and serum creatinine at referral were sufficient to predict survival. Almost 50% (15/31) of the deceased accelerated hypertensives died of acute myocardial infarction. Mean survival after referral was estimated as 18 years for accelerated hypertensives (mean referral age 52 years) and 21 years for other hypertensives (mean referral age 48 years). Blood pressure fell most during the first year of treatment, and declined steadily thereafter. Systolic blood pressure fell by a mean of 50 mmHg and diastolic pressure by 30 mmHg in the first year, and at about 2 (diastolic) and 1 (systolic) mmHg/year for the next 10 years. Thus although the prognosis for accelerated hypertensives is not quite as good as for other hypertensives, with suitable care they can survive for a considerable period.
Authors:
J Webster; J C Petrie; T A Jeffers; H G Lovell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Quarterly journal of medicine     Volume:  86     ISSN:  0033-5622     ISO Abbreviation:  Q. J. Med.     Publication Date:  1993 Aug 
Date Detail:
Created Date:  1993-11-15     Completed Date:  1993-11-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401027     Medline TA:  Q J Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  485-93     Citation Subset:  IM    
Affiliation:
Department of Medicine and Therapeutics, University of Aberdeen, Foresterhill, UK.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Blood Pressure
Cause of Death
Female
Humans
Hypertension / mortality*,  physiopathology
Life Tables
Male
Middle Aged
Prognosis
Referral and Consultation
Risk Factors
Scotland / epidemiology
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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