Document Detail

Acardiac twin with advanced brain development and a minor form of holoprosencephaly and intracerebral retina-like pigmented tissue: a case report and review of the literature.
MedLine Citation:
PMID:  21488711     Owner:  NLM     Status:  Publisher    
Abstract The development of an acardiac twin in a monochorionic multiple pregnancy is a rare and severe complication of abnormal placental vascular anastomoses. These malformed fetuses present with a very bizarre morphology and a plethora of different malformations. However, all acardiac twins show either a complete absence or a rudimental anlage of the heart. Cerebral development is usually poor. We report - according to our review of the literature - for the first time a very unusual case of an acardius with features of an acardius amorphus and acormus (fused head, malformed axial skeleton without macroscopically detectable internal organs) with lobar holoprosencephaly and intracerebral pigmented retina-like tissue.
Sebastian Huss; Florian Fronhoffs; Ulrich Gembruch; Karin U Loeffler; Mark Born; Marco Gessi; Klaus Kuchelmeister; Annette M Müller
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-13
Journal Detail:
Title:  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society     Volume:  -     ISSN:  1093-5266     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9809673     Medline TA:  Pediatr Dev Pathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
1 University Clinic Bonn.
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