Document Detail

Acanthamoeba keratitis and infectious crystalline keratopathy.
MedLine Citation:
PMID:  3314824     Owner:  NLM     Status:  MEDLINE    
Two cases of Acanthamoeba keratitis and infectious crystalline keratopathy, occurring simultaneously, are presented. Three and 12 months after initiating topical corticosteroid therapy in cases 1 and 2, respectively, alpha-hemolytic Streptococcus viridans was cultured from each cornea. Topical corticosteroid therapy was initiated for the treatment of an annular stromal opacity, presumably secondary to herpes simplex keratitis. Acanthamoeba was identified in culture following penetrating keratoplasty in case 1, and Acanthamoeba polyphaga, Acanthamoeba rhysodes, and Acanthamoeba castellanii were identified using indirect fluorescent antibody staining in case 2. Histopathologic examination and electron microscopy demonstrated sheets of cocci within stromal lamellae characteristic of infectious crystalline keratopathy and double-walled encysted organisms typical of Acanthamoeba. These case reports alert one to the possibility of developing bacterial keratitis, such as infectious crystalline keratopathy, following the use of topical corticosteroids for the treatment of Acanthamoeba keratitis.
R M Davis; R P Schroeder; J J Rowsey; H G Jensen; R C Tripathi
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of ophthalmology     Volume:  105     ISSN:  0003-9950     ISO Abbreviation:  Arch. Ophthalmol.     Publication Date:  1987 Nov 
Date Detail:
Created Date:  1987-12-01     Completed Date:  1987-12-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7706534     Medline TA:  Arch Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1524-7     Citation Subset:  AIM; IM    
Department of Ophthalmology, Dean A. McGee Eye Institute, University of Oklahoma, Oklahoma City.
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MeSH Terms
Adrenal Cortex Hormones / therapeutic use
Corneal Diseases / complications*,  pathology
Corneal Transplantation
Keratitis / complications,  etiology*,  pathology,  therapy
Microscopy, Electron
Streptococcal Infections / complications*,  pathology
Reg. No./Substance:
0/Adrenal Cortex Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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