Document Detail


Acanthamoeba keratitis in the south of Sweden.
MedLine Citation:
PMID:  9017049     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eight patients with Acanthamoeba keratitis were diagnosed and treated at our clinic between February 1991 and February 1993. Five of these were contact lens wearers, two had suffered recent corneal trauma and one had recently undergone penetrating keratoplasty. The diagnoses were based on both culture and histological examination of biopsy material in three cases, on culture alone in two cases and on histological examination alone in three cases. In all but one primary treatment was Propamidine isethionate and Neomycin/Polymyxin B topically and Ketoconazole orally. Because of poor healing three patients additionally received Paromomycin and Miconazole or Clotrimazol topically; two of these were further treated with Polyhexamethylene biguanide topically. The interval from initial symptoms to accurate diagnoses varied from one to eleven months. In one patient the eye could not be saved; in the remaining patients visual acuity after healing ranged from hand movements to 1.0.
Authors:
A Skarin; I Florén; K Kiss; H Miörner; U Stenevi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta ophthalmologica Scandinavica     Volume:  74     ISSN:  1395-3907     ISO Abbreviation:  Acta Ophthalmol Scand     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-03-31     Completed Date:  1997-03-31     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  9507578     Medline TA:  Acta Ophthalmol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  593-7     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, University Hospital of Lund, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Acanthamoeba / isolation & purification
Acanthamoeba Keratitis / drug therapy,  epidemiology*,  etiology,  pathology
Adult
Aged
Amebicides / therapeutic use
Animals
Anti-Bacterial Agents
Antifungal Agents / therapeutic use
Biopsy
Cornea / drug effects,  parasitology,  pathology
Drug Therapy, Combination / therapeutic use
Female
Humans
Incidence
Male
Middle Aged
Retrospective Studies
Sweden / epidemiology
Chemical
Reg. No./Substance:
0/Amebicides; 0/Anti-Bacterial Agents; 0/Antifungal Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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