Document Detail

Academic and Nonacademic Laboratories Perform Equally on CIQC Immunohistochemistry Proficiency Testing.
MedLine Citation:
PMID:  23765534     Owner:  NLM     Status:  In-Data-Review    
Objectives: To test whether academic centers (ACs) are more successful than nonacademic centers (NACs) in immunohistochemistry (IHC) external quality assessment challenges in the Canadian Immunohistochemistry Quality Control (CIQC) program. Methods: Results of 9 CIQC challenges for breast cancer marker (BM) and various non-breast cancer marker (NBM) tests were examined. Success rates were compared between AC/NAC laboratories and those located in small or large cities. Performance was also correlated with annual IHC case volumes. Results: There was no statistically significant difference in performance in any of the comparisons. However, overall performance on BM was significantly better (P < .0001, t test) than on NBM tests regardless of AC/NAC nature or city size. The mean failure rate on NBM was approximately twice that of BM tests. Conclusion: Our results suggest that recent emphasis on breast hormone IHC quality assurance has led to improved test quality.
Zhongchuan Will Chen; Heather Neufeld; Maria A Copete; John Garratt; C Blake Gilks; Emina E Torlakovic
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of clinical pathology     Volume:  140     ISSN:  1943-7722     ISO Abbreviation:  Am. J. Clin. Pathol.     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370470     Medline TA:  Am J Clin Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  55-60     Citation Subset:  AIM; IM    
Dept of Laboratory Hematology, University Health Network, 200 Elizabeth St, Rm 11E-411, Toronto, Ontario M5G 2C4, Canada; e-mail:
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