Document Detail


Abuse of buprenorphine in the United States: 2003-2005.
MedLine Citation:
PMID:  18018814     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study examines trends in the reported abuse of two sublingual buprenorphine products, Subutex and Suboxone, in the United States. Quarterly counts of abuse cases were obtained from 18 regional poison control centers (PCCS) for 2003-2005. Seventy-seven abuse cases were reported, of which 7.8 percent involved Subutex and 92.2 percent involved Suboxone. The average quarterly ratio of abuse cases per 1,000 prescriptions dispensed was 0.08 (SD +/- 0.09) for Subutex, and 0.16 (SD +/- 0.08) for Suboxone. Findings suggest that these sublingual buprenorphine formulations have a low rate of abuse based on toxico-surveillance data.
Authors:
Meredith Y Smith; J Elise Bailey; George E Woody; Herbert D Kleber
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of addictive diseases     Volume:  26     ISSN:  1055-0887     ISO Abbreviation:  J Addict Dis     Publication Date:  2007  
Date Detail:
Created Date:  2007-11-16     Completed Date:  2008-01-18     Revised Date:  2008-05-12    
Medline Journal Info:
Nlm Unique ID:  9107051     Medline TA:  J Addict Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  107-11     Citation Subset:  IM    
Affiliation:
Risk Management & Health Policy, Purdue Pharma L.P., Stamford, CT 06901-3431, USA. meredith.smith@pharma.com
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MeSH Terms
Descriptor/Qualifier:
Administration, Sublingual
Adult
Buprenorphine / administration & dosage,  therapeutic use*
Female
Humans
Male
Narcotics / therapeutic use*
Opioid-Related Disorders / epidemiology*,  rehabilitation*
Registries
Chemical
Reg. No./Substance:
0/Narcotics; 52485-79-7/Buprenorphine
Comments/Corrections
Comment In:
J Addict Dis. 2007;26(3):1-3   [PMID:  18018803 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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