| Absorption spectroscopy in microfluidic flow cells using a metal clad leaky waveguide device with a porous gel waveguide layer. | |
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MedLine Citation:
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PMID: 23152951 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Broadband absorption spectroscopy is advantageous because the full spectral profile of an analyte can permit identification of species. This work for the first time investigates the feasibility of a metal clad leaky waveguide (MCLW) device to obtain an absorption spectrum of an analyte of interest, methylene blue, using a white light source in a microfluidic flow cell. The MCLW device comprises a porous low refractive index gel, agarose, deposited on a titanium coated glass slide. The device was capable of detecting 2.3 μM of methylene blue at a wavelength of 650 nm. The corresponding minimum detectable absorbance is 1.6 × 10(-1) cm(-1). In comparison to commonly used detection devices the MCLW is simpler, robust, easier to fabricate and can be easily interfaced to microfluidic devices. It was also possible to store the MCLW devices dry for up to a year and rehydrate them in 30 s to a working condition. |
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Authors:
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Ruchi Gupta; Behnam Bastani; N J Goddard; Bruce Grieve |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-11-14 |
Journal Detail:
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Title: The Analyst Volume: - ISSN: 1364-5528 ISO Abbreviation: Analyst Publication Date: 2012 Nov |
Date Detail:
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Created Date: 2012-11-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372652 Medline TA: Analyst Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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School of Chemical Engineering and Analytical Science, University of Manchester, Manchester, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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