Document Detail


Absorption of non heme iron in typical and standard meals using extrinsically labeled iron 59Fe.
MedLine Citation:
PMID:  15270181     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To study the bioavailibility of nonheme iron from standard and test meals in Pakistani adults and to determine iron absorption using extrinsically tagged iron 59Fe. SUBJECTS AND METHODS: Nonheme iron absorption was measured from standard and test meals in ten healthy individuals. Total calories, carbohydrates, proteins, fats, ascorbic acid, total iron, phytate and ascorbic acid content were determined in both meals. Retention of iron was detected by whole body counting using gamma counter before and after administration of standard, test meals and reference dose. RESULTS: Iron absorption with test meal was 13% and after adjustment with serum ferritin and reference dose was 16.5 % and 14% respectively. The absorption of standard meal was 6.7% which after adjustment with serum ferritin and reference dose was 8.8% and 6.9% respectively. The iron and ascorbic acid content of test meal was 6.5 mg and 5.7 mg respectively while phytate phosphorus content was 114 mg. The iron and ascorbic acid content of standard meal was 1.3 mg and 2.4 mg respectively while phytate phosphorus content was 137 mg. CONCLUSION: This evaluated absorption from one of the typical Pakistani diet compared to the standard meal was better. This shows that there are some other physiological factors that lead to iron deficiency anemia in Pakistan.
Authors:
A Jaleel; M A Rahman; R A Khan; J Aftab
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  JPMA. The Journal of the Pakistan Medical Association     Volume:  54     ISSN:  0030-9982     ISO Abbreviation:  J Pak Med Assoc     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-07-23     Completed Date:  2004-09-22     Revised Date:  2008-02-12    
Medline Journal Info:
Nlm Unique ID:  7501162     Medline TA:  J Pak Med Assoc     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  244-8     Citation Subset:  IM    
Affiliation:
Department of Biochemistry and Nuclear Medicine, Ziauddin Medical University, Karachi.
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MeSH Terms
Descriptor/Qualifier:
Absorption
Adult
Biological Availability
Diet*
Humans
Iron Radioisotopes / pharmacokinetics
Middle Aged
Nonheme Iron Proteins / pharmacokinetics*
Reference Values
Chemical
Reg. No./Substance:
0/Iron Radioisotopes; 0/Nonheme Iron Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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