Document Detail


Absorption of nicotine from small cigars.
MedLine Citation:
PMID:  620474     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The absorption of nicotine from cigars was measured in 7 male subjects who each smoked a single small cigar containing 14C-nicotine. The proportion of nicotine in the mainstream smoke delivered to the smoker's mouth was greater than that observed for cigarettes, but the proportion of nicotine in the cigar smoke which was retained by the smoker was about the same. The total dose of nicotine retained varied between 1 and 4.5 mg. Arterial plasma concentrations of nicotine were as high as those achieved by cigarette smoking but rose more slowly. Some nicotine from small cigars is absorbed by inhalation of the smoke into the lungs and some by buccal absorption.
Authors:
A Armitage; C Dollery; T Houseman; E Kohner; P J Lewis; D Turner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical pharmacology and therapeutics     Volume:  23     ISSN:  0009-9236     ISO Abbreviation:  Clin. Pharmacol. Ther.     Publication Date:  1978 Feb 
Date Detail:
Created Date:  1978-03-21     Completed Date:  1978-03-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372741     Medline TA:  Clin Pharmacol Ther     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  143-51     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Absorption
Adult
Cotinine / blood
Heart Rate
Humans
Male
Middle Aged
Nicotine / blood,  metabolism*
Respiration
Smoking / metabolism*,  physiopathology
Time Factors
Chemical
Reg. No./Substance:
486-56-6/Cotinine; 54-11-5/Nicotine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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