Document Detail


Absent right atrioventricular connection and double-inlet ventricle due to an unbalanced familial 8:13 chromosome translocation: a cautionary tale.
MedLine Citation:
PMID:  6462930     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A two-year-old child who had had palliative surgery as a neonate for an absent right atrioventricular connection and double-inlet ventricle was shown to be developmentally retarded. Trisomy for the short arm of chromosome 8 was demonstrated, resulting from a familial 8:13 translocation, with a high risk of recurrence. Although the specific features of this case are unique, it illustrates the importance of chromosome analysis in any dysmorphic infant whose heart defect places prolonged survival in doubt.
Authors:
J Burn; M Baraitser; D T Hughes; P Saldana-Garcia; J F Taylor
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric cardiology     Volume:  5     ISSN:  0172-0643     ISO Abbreviation:  Pediatr Cardiol     Publication Date:    1984 Jan-Mar
Date Detail:
Created Date:  1984-08-29     Completed Date:  1984-08-29     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  8003849     Medline TA:  Pediatr Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  55-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Child, Preschool
Chromosomes, Human, 13-15*
Chromosomes, Human, 6-12 and X*
Female
Heart Atria / abnormalities
Heart Catheterization
Heart Defects, Congenital / genetics*
Heart Ventricles / abnormalities
Humans
Infant, Newborn
Noonan Syndrome / pathology
Translocation, Genetic*
Trisomy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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