| Absence of terminal telomeric FISH signals in chromosomes from immortal Chinese hamster cells. | |
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MedLine Citation:
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PMID: 7835095 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In contrast to normal Chinese hamster cells, terminal telomeric signals were not detectable by fluorescence in situ hybridization (FISH) in their immortalized counterparts, even when a sensitive cooled CCD camera was used for acquiring FISH images. Since the telomeres were detectable by FISH in immortal human cells, this suggests that hamster and human cells might have different mechanisms of telomere processing. |
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Authors:
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P Slijepcevic; P E Bryant |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cytogenetics and cell genetics Volume: 69 ISSN: 0301-0171 ISO Abbreviation: Cytogenet. Cell Genet. Publication Date: 1995 |
Date Detail:
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Created Date: 1995-02-27 Completed Date: 1995-02-27 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0367735 Medline TA: Cytogenet Cell Genet Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 87-9 Citation Subset: IM |
Affiliation:
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Department of Pathology, University of Cambridge, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Base Sequence CHO Cells Cell Line, Transformed Chromosome Banding* Chromosome Mapping* Cricetinae Cricetulus Female Humans Hybrid Cells In Situ Hybridization, Fluorescence / methods* Microscopy, Confocal Repetitive Sequences, Nucleic Acid* Telomere / ultrastructure* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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