Document Detail

Absence status epilepticus resulting from metrizamide and omnipaque myelography.
MedLine Citation:
PMID:  3396204     Owner:  NLM     Status:  MEDLINE    
Two cases of absence status are described, one case following metrizamide myelography and the other from omnipaque myelography. Metrizamide has been well known to cause convulsive seizures even in patients without epilepsy. The exact mechanism is not known but appears to be direct neuronal toxic effects possibly due to competitive inhibition of hexokinase activity. The acute confusional state following myelography from water soluble agents is reviewed. In view of the difficulty in clinical diagnosis and the excellent response to anticonvulsant therapy, the possibility of this clinical entity should be specifically excluded by EEG in any person suffering from prolonged confusion following myelography with water soluble agents.
I Ahmed; R Pepple; R P Jones
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical EEG (electroencephalography)     Volume:  19     ISSN:  0009-9155     ISO Abbreviation:  Clin Electroencephalogr     Publication Date:  1988 Jan 
Date Detail:
Created Date:  1988-08-26     Completed Date:  1988-08-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0236454     Medline TA:  Clin Electroencephalogr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  37-42     Citation Subset:  IM    
University of Missouri School of Medicine, Kansas City.
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MeSH Terms
Iohexol / adverse effects*
Metrizamide / adverse effects*
Middle Aged
Myelography / adverse effects*
Status Epilepticus / chemically induced*,  physiopathology
Reg. No./Substance:
31112-62-6/Metrizamide; 66108-95-0/Iohexol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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