Document Detail


Absence of mutagenic activity and a short-term toxicity study of beet pigments as food colorants.
MedLine Citation:
PMID:  7034685     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Beet colorant was tested for mutagenic activity in five S. typhimurium strains. The absence of mutagenic activity was found with or without S-9 rat liver fractions. Groups of six rats were fed red beet colorant preparations containing 2,000 ppm betalains in the diet for 7 days. No significant differences were noted in body weight gains, feed consumption, or gross pathological alterations compared to the controls. These preliminary toxicological results indicate the potential usage of betalain pigments as a food colorant, but further long term investigations are warranted.
Authors:
J H von Elbe; S J Schwartz
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of toxicology     Volume:  49     ISSN:  0340-5761     ISO Abbreviation:  Arch. Toxicol.     Publication Date:  1981 Nov 
Date Detail:
Created Date:  1982-03-13     Completed Date:  1982-03-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0417615     Medline TA:  Arch Toxicol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  93-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Betalains
Body Weight / drug effects
Female
Food Coloring Agents / toxicity*
Lethal Dose 50
Male
Mutagenicity Tests
Pigments, Biological / toxicity*
Quaternary Ammonium Compounds*
Rats
Rats, Inbred Strains
Salmonella typhimurium / drug effects
Vegetables*
Chemical
Reg. No./Substance:
0/Food Coloring Agents; 0/Pigments, Biological; 0/Quaternary Ammonium Compounds; 37279-84-8/Betalains

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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