Document Detail


Absence of gender effect on amygdala volume in temporal lobe epilepsy.
MedLine Citation:
PMID:  20920847     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Sexual dimorphism has already been described in temporal lobe epilepsy with mesial temporal sclerosis (TLE-MTS). This study evaluated the effect of gender on amygdala volume in patients with TLE-MTS. One hundred twenty-four patients with refractory unilateral or bilateral TLE-MTS who were being considered for epilepsy surgery underwent a comprehensive presurgical evaluation and MRI. Amygdalas of 67 women (27 with right; 32 with left, and 8 with bilateral TLE) and 57 men (22 with right, 30 with left, and 5 with bilateral TLE) were manually segmented. Significant ipsilateral amygdala volume reduction was observed for patients with right and left TLE. No gender effect on amygdala volume was observed. Contralateral amygdalar asymmetry was observed for patients with right and left TLE. Although no gender effect was observed on amygdala volume, ipsilateral amygdala volume reductions in patients with TLE might be related to differential rates of cerebral maturation between hemispheres.
Authors:
Ivaldo Silva; Katia Lin; Andrea P Jackowski; Ricardo da Silva Centeno; Magali L Pinto; Henrique Carrete; Elza M Yacubian; Débora Amado
Related Documents :
8598187 - Two patients with juvenile myoclonic epilepsy and nonconvulsive status epilepticus.
11733667 - Effects of sevoflurane and isoflurane on electrocorticographic activities in patients w...
19556167 - Lateralizing seizure focus in presurgical patients with temporal lobe epilepsy: utility...
508147 - Facial recognition in patients with focal brain lesions.
7962747 - Congenital "self-healing" langerhans cell histiocytosis: the need for long-term follow-up.
24426837 - Autograft and allograft unite similarly in lateral column lengthening for adult acquire...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Epilepsy & behavior : E&B     Volume:  19     ISSN:  1525-5069     ISO Abbreviation:  Epilepsy Behav     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-12-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100892858     Medline TA:  Epilepsy Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  501-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Inc. All rights reserved.
Affiliation:
Gynecology Department, Universidade Federal de São Paulo, São Paulo, Brazil. ivaldo.silva@gmail.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Administration of lithium and magnesium chloride inhibited tolerance to the anticonvulsant effect of...
Next Document:  Twice vs three-times daily antibiotics in the treatment of pulmonary exacerbations of cystic fibrosi...